维生素D与慢性疾病。
Vitamin D and Chronic Diseases.
作者信息
Wang Hanmin, Chen Weiwen, Li Dongqing, Yin Xiaoe, Zhang Xiaode, Olsen Nancy, Zheng Song Guo
机构信息
1Division of Endocrinology, Quqing First Hospital at Kunming Medical University, Qujing, Yunan 655400, China.
2Expert Workstation, Quqing First Hospital at Kunming Medical University, Qujing, Yunan 655400, China.
出版信息
Aging Dis. 2017 May 2;8(3):346-353. doi: 10.14336/AD.2016.1021. eCollection 2017 May.
Abstract
Vitamin D is one of the essential nutrients to sustain the human health. As a member of the steroid hormone family, it has a classic role in regulating metabolism of calcium and a non-classic role in affecting cell proliferation and differentiation. Epidemiological studies have shown that 25OHD deficiency is closely associated with common chronic diseases such as bone metabolic disorders, tumors, cardiovascular diseases, and diabetes. 25OHD deficiency is also a risk factor for neuropsychiatric disorders and autoimmune diseases. 25OHD deficiency is highly prevalent in the world. It is therefore necessary to know the adverse health effects of 25OHD deficiency, and to design interventions and early treatments for those who are likely to have low levels of 25OHD.
摘要
维生素D是维持人体健康的必需营养素之一。作为类固醇激素家族的一员，它在调节钙代谢方面具有经典作用，在影响细胞增殖和分化方面具有非经典作用。流行病学研究表明，25羟维生素D缺乏与骨代谢紊乱、肿瘤、心血管疾病和糖尿病等常见慢性病密切相关。25羟维生素D缺乏也是神经精神疾病和自身免疫性疾病的一个危险因素。25羟维生素D缺乏在世界范围内高度流行。因此，有必要了解25羟维生素D缺乏对健康的不良影响，并为那些可能25羟维生素D水平较低的人群设计干预措施和早期治疗方法。
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