在乳牙根管中鉴定出的粪肠球菌会是牙髓治疗失败的一个原因吗？
Can the Enterococcus faecalis identified in the root canals of primary teeth be a cause of failure of endodontic treatment?
作者信息
Cancio Viviane, Carvalho Ferreira Dennis de, Cavalcante Fernanda Sampaio, Rosado Alexandre Soares, Teixeira Lúcia Martins, Braga Oliveira Queila, Barcelos Roberta, Gleiser Rogerio, Santos Henrique Fragoso, Dos Santos Kátia Regina Netto, Primo Laura Guimarães
机构信息
a Department of Pediatric Dentistry and Orthodontics, School of Dentistry , Federal University of Rio de Janeiro , Rio de Janeiro , Brazil.
b Department of Medical Microbiology, Institute of Microbiology , Federal University of Rio de Janeiro , Rio de Janeiro , Brazil.
出版信息
Acta Odontol Scand. 2017 Aug;75(6):423-428. doi: 10.1080/00016357.2017.1328742. Epub 2017 Jun 5.
OBJECTIVE
This study investigated the presence of Enterococcus faecalis in primary teeth with primary root canal infections and related to the possible failure of pulpectomy outcome after 36 months.
MATERIAL AND METHODS
Root canal samples were obtained from 25 out of 244 patients using the sterile paper cone method. The identification of E. faecalis was done with culture and molecular tests using species-specific 16S rRNA gene-based polymerase chain reaction (PCR). After 36 months, the pulpectomy outcome was evaluated.
RESULTS
Enterococcus faecalis was found in five (20%) samples, and dental caries were the cause of primary infection in all of them. Pulpectomy outcome was evaluated only in teeth that completed the entire clinical protocol and were followed up to 36 months (n = 8). From these, 75% (n = 6) were successful and 25% (n = 2) failed. E. faecalis was present in 50% of both successful and failed cases.
CONCLUSIONS
Enterococcus faecalis was not related to the failure of endodontic treatment of primary teeth.
目的
本研究调查了患有原发性根管感染的乳磨牙中粪肠球菌的存在情况，并探讨其与36个月后根管治疗失败的可能关系。
材料与方法
采用无菌纸尖法从244例患者中的25例获取根管样本。使用基于种特异性16S rRNA基因的聚合酶链反应（PCR）通过培养和分子检测对粪肠球菌进行鉴定。36个月后，评估根管治疗的结果。
结果
在5份（20%）样本中发现了粪肠球菌，且所有样本中龋齿均为原发性感染的原因。仅对完成整个临床方案并随访至36个月的牙齿（n = 8）评估根管治疗结果。其中，75%（n = 6）成功，25%（n = 2）失败。成功和失败病例中均有50%存在粪肠球菌。
结论
粪肠球菌与乳磨牙根管治疗失败无关。
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