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猪甲状腺中的碘甲状腺原氨酸含量。

Iodothyronine content in the pig thyroid gland.

作者信息

Nowak G

出版信息

Comp Biochem Physiol A Comp Physiol. 1985;80(2):183-6. doi: 10.1016/0300-9629(85)90538-9.

DOI:10.1016/0300-9629(85)90538-9
PMID:2858300
Abstract

An analysis has been carried out on the contents and reciprocal proportions of three principal iodothyronines (T4, T3 and rT3) in the thyroids of fed and fasted piglets of 8-10 wk and in adult pigs. The mean T4 concentration averaged 62.0 +/- nmol/100 mg wet tissue (in adults: 18.5 +/- 4.3 nmol/100 mg tissue); T3, 9.5 +/- 0.9 nmol/100 mg tissue (in adults: 1.58 +/- 0.2 nmol/100 mg tissue); rT3, 3.0 +/- 0.3 nmol/100 mg tissue. The reciprocal ratios of the hormones in the piglets' thyroids were: for T3:T4, 0.150 (in adults, 0.114) and for rT3:T4, 0.050 (in adults, 0.023). Mean T4:T3:rT3 ratio in piglets and adult pigs was 20.5:3.1:1 and 66.1:5.6:1, respectively. The results from all examined iodothyronines, show the higher absolute concentration in piglets' than in adult pigs' thyroid tissue, while the reciprocal proportions of the hormones reveal smaller T4 thyroid contents (comparing with T3 and rT3) in piglets than in adults. No changes of absolute thyroidal contents or reciprocal ratios of the iodothyronines were observed in fed and fasted piglets. In a comparison, the pig thyroid contains more triiodothyronine and a higher ratio T3:T4 than that in some other species.

摘要

对8 - 10周龄的哺乳和禁食仔猪以及成年猪甲状腺中三种主要碘甲状腺原氨酸(T4、T3和rT3)的含量及相互比例进行了分析。T4平均浓度为62.0±nmol/100mg湿组织(成年猪:18.5±4.3nmol/100mg组织);T3为9.5±0.9nmol/100mg组织(成年猪:1.58±0.2nmol/100mg组织);rT3为3.0±0.3nmol/100mg组织。仔猪甲状腺中激素的相互比例为:T3:T4为0.150(成年猪为0.114),rT3:T4为0.050(成年猪为0.023)。仔猪和成年猪中T4:T3:rT3的平均比例分别为20.5:3.1:1和66.1:5.6:1。所有检测的碘甲状腺原氨酸结果显示,仔猪甲状腺组织中的绝对浓度高于成年猪,而激素的相互比例显示,与成年猪相比,仔猪甲状腺中T4的含量较少(与T3和rT3相比)。在哺乳和禁食的仔猪中,未观察到甲状腺中碘甲状腺原氨酸的绝对含量或相互比例发生变化。相比之下,猪甲状腺中含有的三碘甲状腺原氨酸更多,T3:T4的比例高于其他一些物种。

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