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中骨盆部位行助产术分娩后围生期和孕产妇的发病率和死亡率。

Perinatal and maternal morbidity and mortality after attempted operative vaginal delivery at midpelvic station.

机构信息

School of Population and Public Health (Muraca, Lisonkova, Joseph); Department of Obstetrics & Gynaecology (Muraca, Sabr, Lisonkova, Skoll, Cundiff, Joseph); Department of Statistics (Brant), The University of British Columbia, Vancouver, BC; Department of Obstetrics and Gynaecology (Sabr), King Saud University, Riyadh, Saudi Arabia

School of Population and Public Health (Muraca, Lisonkova, Joseph); Department of Obstetrics & Gynaecology (Muraca, Sabr, Lisonkova, Skoll, Cundiff, Joseph); Department of Statistics (Brant), The University of British Columbia, Vancouver, BC; Department of Obstetrics and Gynaecology (Sabr), King Saud University, Riyadh, Saudi Arabia.

出版信息

CMAJ. 2017 Jun 5;189(22):E764-E772. doi: 10.1503/cmaj.161156.

Abstract

BACKGROUND

Increased use of operative vaginal delivery (i.e., forceps or vacuum application), of which 20% occurs at midpelvic station, has been advocated to reduce the rate of cesarean delivery. We aimed to quantify severe perinatal and maternal morbidity and mortality associated with attempted midpelvic operative vaginal delivery.

METHODS

We studied all term singleton deliveries in Canada between 2003 and 2013, by attempted midpelvic operative vaginal or cesarean delivery with labour (with and without prolonged second stage). The primary outcomes were composite severe perinatal morbidity and mortality (e.g., convulsions, assisted ventilation, severe birth trauma and perinatal death), and composite severe maternal morbidity and mortality (e.g., severe postpartum hemorrhage, shock, sepsis, cardiac complications, acute renal failure and death).

RESULTS

The study population included 187 234 deliveries. Among women with dystocia and prolonged second stage of labour, midpelvic operative vaginal delivery was associated with higher rates of severe perinatal morbidity and mortality compared with cesarean delivery (forceps, adjusted odds ratio [AOR] 1.81, 95% confidence interval [CI] 1.24 to 2.64; vacuum, AOR 1.81, 95% CI 1.17 to 2.80; sequential instruments, AOR 3.19, 95% CI 1.73 to 5.88), especially with higher rates of severe birth trauma. Rates of severe maternal morbidity and mortality were not significantly different after operative vaginal delivery, although rates of obstetric trauma were higher (forceps, AOR 4.51, 95% CI 4.04 to 5.02; vacuum, AOR 2.70, 95% CI 2.35 to 3.09; sequential instruments, AOR 4.24, 95% CI 3.46 to 5.19). Among women with fetal distress, similar associations were seen for severe birth trauma and obstetric trauma, although vacuum was associated with lower rates of severe maternal morbidity and mortality (AOR 0.52, 95% CI 0.33 to 0.80). Associations tended to be stronger among women without a prolonged second stage.

INTERPRETATION

Midpelvic operative vaginal delivery is associated with higher rates of severe birth trauma and obstetric trauma, whereas overall rates of severe perinatal and maternal morbidity and mortality vary by indication and operative instrument.

摘要

背景

越来越多地使用产道手术分娩(即产钳或吸引器助产),其中 20%发生在中骨盆部位,以降低剖宫产率。我们旨在量化与尝试中骨盆产道手术分娩相关的严重围产期和产妇发病率和死亡率。

方法

我们研究了 2003 年至 2013 年期间加拿大所有足月单胎分娩,包括尝试中骨盆产道手术分娩或剖宫产分娩伴或不伴第二产程延长。主要结局是复合严重围产期发病率和死亡率(如惊厥、辅助通气、严重出生创伤和围产儿死亡)和复合严重产妇发病率和死亡率(如严重产后出血、休克、败血症、心脏并发症、急性肾衰竭和死亡)。

结果

研究人群包括 187234 例分娩。在有难产和第二产程延长的妇女中,与剖宫产分娩相比,中骨盆产道手术分娩与更高的严重围产期发病率和死亡率相关(产钳,校正比值比 [OR]1.81,95%置信区间 [CI]1.24 至 2.64;吸引器,OR1.81,95%CI1.17 至 2.80;顺序器械,OR3.19,95%CI1.73 至 5.88),尤其是严重出生创伤的发生率更高。产道手术后严重产妇发病率和死亡率无显著差异,但产科创伤发生率较高(产钳,OR4.51,95%CI4.04 至 5.02;吸引器,OR2.70,95%CI2.35 至 3.09;顺序器械,OR4.24,95%CI3.46 至 5.19)。在胎儿窘迫的妇女中,严重出生创伤和产科创伤也存在类似的关联,尽管吸引器与较低的严重产妇发病率和死亡率相关(OR0.52,95%CI0.33 至 0.80)。这些关联在第二产程无延长的妇女中更为明显。

结论

中骨盆产道手术分娩与较高的严重出生创伤和产科创伤发生率相关,而严重围产期和产妇发病率和死亡率的总体发生率因适应证和手术器械而异。

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