Kadiyala Pavan Kumar, Kadiyala Lakshmi Deepthi
Department of Psychiatry, Siddhartha Medical College, Vijayawada, Andhra Pradesh, India.
Department of Anaesthesia, JJM Medical College, Davanagere, Karnataka, India.
Indian J Anaesth. 2017 May;61(5):373-380. doi: 10.4103/ija.IJA_132_17.
Despite advances in pharmacotherapy, electroconvulsive therapy (ECT) remains a mainstay treatment option in psychiatry since its introduction in 1930s. It can be used primarily in severe illnesses when there is an urgent need for treatment or secondarily after failure or intolerance to pharmacotherapy. The 'unmodified' technique of ECT was practised initially, with a high incidence of musculoskeletal complications. Several modifications including general anaesthesia and muscle relaxation are used to increase the safety and patient acceptability of ECT. Various anaesthetic techniques including medications are considered to provide adequate therapeutic seizure, simultaneously controlling seizure-induced haemodynamic changes and side effects. A brief review of literature on choice of these anaesthetic techniques is discussed. This article is intended to reinforce the knowledge of clinicians, who may have limited exposure to ECT procedure. Importance is given to the recent updates on the role of induction agents in potentiating therapeutic response to ECT in psychiatric disorders.
尽管药物治疗取得了进展,但自20世纪30年代引入以来,电休克疗法(ECT)仍然是精神病学中的主要治疗选择。它主要用于急需治疗的严重疾病,或在药物治疗失败或不耐受后作为二线治疗。ECT最初采用的是“未改良”技术,肌肉骨骼并发症的发生率很高。包括全身麻醉和肌肉松弛在内的几种改良方法被用于提高ECT的安全性和患者接受度。包括药物在内的各种麻醉技术被认为可以提供足够的治疗性癫痫发作,同时控制癫痫发作引起的血流动力学变化和副作用。本文对这些麻醉技术的选择相关文献进行了简要综述。本文旨在强化临床医生的知识,他们可能对ECT程序接触有限。本文重点介绍了诱导剂在增强ECT对精神疾病治疗反应方面作用的最新进展。