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帕金森病围手术期舌下含服左旋多巴:一种有用的替代方法!

Perioperative sublingual levodopa in Parkisnon's Disease: A useful alternative!

作者信息

Bhirud Pritee H, Kate Jalpa Arvind

机构信息

Department of Anaesthesia, Bhabha Atomic Research Centre Hospital, Mumbai, Maharashtra, India.

出版信息

Indian J Anaesth. 2017 May;61(5):432-434. doi: 10.4103/ija.IJA_178_17.

DOI:10.4103/ija.IJA_178_17
PMID:28584355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5444224/
Abstract

Timely administration of dopamine agonists is of the essence in Parkinson's disease. The perioperative period especially for abdominal surgeries under general anaesthesia poses a challenge to oral drug administration. Alternatives such as rotigotine patches and subcutaneous apomorphine administration have been described but unavailability restricts their use. Sublingual administration of tablet levodopamine as an alternative worked well in our patients and we would like to describe the same.

摘要

及时给予多巴胺激动剂对帕金森病至关重要。围手术期,尤其是全身麻醉下的腹部手术,对口服药物给药构成挑战。已描述了如罗替戈汀贴剂和皮下注射阿扑吗啡等替代方法,但可用性限制了它们的使用。在我们的患者中,舌下含服左旋多巴片作为替代方法效果良好,我们在此进行描述。

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Perioperative sublingual levodopa in Parkisnon's Disease: A useful alternative!帕金森病围手术期舌下含服左旋多巴:一种有用的替代方法!
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本文引用的文献

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Design and evaluation of levodopa methyl ester intranasal delivery systems.左旋多巴甲酯经鼻腔给药系统的设计与评价。
J Parkinsons Dis. 2011;1(1):101-7. doi: 10.3233/JPD-2011-10011.
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Parkinson's disease and anaesthesia.帕金森病与麻醉
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[Perioperative management of Parkinson's disease].[帕金森病的围手术期管理]
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Parkinson's disease and anaesthesia.帕金森病与麻醉
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Successful perioperative management of a patient with Parkinson's disease by enteral levodopa administration under propofol anesthesia.在丙泊酚麻醉下通过肠内给予左旋多巴对帕金森病患者进行成功的围手术期管理。
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Using liquid levodopa in the treatment of Parkinson's disease. A practical guide.使用左旋多巴治疗帕金森病。实用指南。
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Impaired absorption of oral levodopa: a major cause for response fluctuations in Parkinson's disease.口服左旋多巴吸收受损:帕金森病反应波动的主要原因
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Subcutaneous and sublingual levodopa methyl ester in Parkinson's disease.帕金森病中皮下及舌下含服左旋多巴甲酯的应用
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