Alhaddad Imad A, Tabbalat Ramzi, Khader Yousef, Al-Mousa Eyas, Izraiq Mahmoud, Nammas Assem, Jarrah Mohammad, Saleh Akram, Hammoudeh Ayman
Department of Cardiovascular, Jordan Hospital, Amman, Jordan.
Department of Cardiology, Khalidi Medical Center, Amman, Jordan.
Heart Views. 2017 Jan-Mar;18(1):3-7. doi: 10.4103/1995-705X.206206.
This is a prospective multicenter registry designed to evaluate the incidence of adverse cardiovascular events in Middle Eastern patients undergoing percutaneous coronary interventions (PCI). The registry was also designed to determine the predictors of poor outcomes in such patients.
We enrolled 2426 consecutive patients who underwent PCI at 12 tertiary care centers in Jordan between January 2013 and February 2014. A case report form was used to record data prospectively at hospital admission, discharge, and 12 months of follow-up. Mean age was 56 ± 11 years, females comprised 21% of the study patients, 62% had hypertension, 53% were diabetics, and 57% were cigarette smokers. Most patients (77%) underwent PCI for acute coronary syndrome. In-hospital and 1-year mortality rates were 0.78% and 1.94%, respectively. Definite or probable stent thrombosis occurred in 9 patients (0.37%) during hospitalization and in 47 (1.94%) at 1 year. Rates of target vessel repeat PCI and coronary artery bypass graft surgery at 1 year were 3.4% and 0.6%, respectively. The multivariate analysis revealed that cardiogenic shock, congestive heart failure, ST-segment deviation, diabetes, and major bleeding were significantly associated with higher risk of 1-year mortality.
In this first large Jordanian registry of Middle Eastern patients undergoing PCI, patients treated were relatively young age population with low in-hospital and 1-year adverse cardiovascular events. Certain clinical features were associated with worse outcomes and may warrant aggressive therapeutic strategies.
这是一项前瞻性多中心注册研究，旨在评估中东地区接受经皮冠状动脉介入治疗（PCI）患者发生不良心血管事件的发生率。该注册研究还旨在确定此类患者预后不良的预测因素。
我们纳入了2013年1月至2014年2月期间在约旦12家三级医疗中心连续接受PCI治疗的2426例患者。使用病例报告表在患者入院、出院及随访12个月时前瞻性记录数据。患者平均年龄为56±11岁，女性占研究患者的21%，62%患有高血压，53%为糖尿病患者，57%为吸烟者。大多数患者（77%）因急性冠状动脉综合征接受PCI治疗。住院死亡率和1年死亡率分别为0.78%和1.94%。住院期间9例患者（0.37%）发生明确或可能的支架血栓形成，1年时为47例（1.94%）。1年时靶血管再次PCI和冠状动脉旁路移植术的发生率分别为3.4%和0.6%。多变量分析显示，心源性休克、充血性心力衰竭、ST段偏移、糖尿病和大出血与1年死亡风险较高显著相关。
在这项约旦首个针对中东地区接受PCI治疗患者的大型注册研究中，接受治疗的患者相对年轻，住院期间和1年不良心血管事件发生率较低。某些临床特征与较差的预后相关，可能需要积极的治疗策略。
