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男性在抗抑郁药物治疗上是否未得到充分治疗而女性是否治疗过度?瑞典一项横断面调查的结果。

Are men under-treated and women over-treated with antidepressants? Findings from a cross-sectional survey in Sweden.

作者信息

Thunander Sundbom Lena, Bingefors Kerstin, Hedborg Kerstin, Isacson Dag

机构信息

Uppsala University, Uppsala, Sweden.

University of Gävle, Gävle, Sweden.

出版信息

BJPsych Bull. 2017 Jun;41(3):145-150. doi: 10.1192/pb.bp.116.054270.

DOI:10.1192/pb.bp.116.054270
PMID:28584650
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5451647/
Abstract

To examine gender differences in self-reported depression and prescribed antidepressants (ADs). The Hospital Anxiety and Depression Scale was used to assess depression, and information on prescribed ADs was obtained from the Swedish Prescribed Drug Register. Depression was reported by 11.7% of the participants (12.3% men and 11.2% women). ADs were prescribed for 7.6% of the participants (5.3% men, 9.8% women). Among men, 1.8% reported depression and used ADs, 10.5% reported depression but did not use ADs, and 3.6% used ADs but did not report depression. The corresponding figures for women were 2.6%, 8.6% and 7.2%. Men report depression to a greater extent than women but are prescribed ADs to a lesser extent, possibly a sign of under-treatment. Women are prescribed ADs without reporting depression more often than men, possibly a sign of over-treatment. Although the causes remain unclear, diagnostic and treatment guidelines should benefit from considering gender differences in these respects.

摘要

研究自我报告的抑郁症及处方抗抑郁药(ADs)方面的性别差异。使用医院焦虑抑郁量表评估抑郁情况,并从瑞典处方药登记处获取处方ADs的信息。11.7%的参与者报告有抑郁症(男性为12.3%,女性为11.2%)。7.6%的参与者被开了ADs(男性为5.3%,女性为9.8%)。在男性中,1.8%报告有抑郁症且使用了ADs,10.5%报告有抑郁症但未使用ADs, 3.6%使用了ADs但未报告有抑郁症。女性的相应数字分别为2.6%、8.6%和7.2%。男性报告抑郁症的比例高于女性,但被开ADs的比例低于女性,这可能是治疗不足的迹象。女性未报告抑郁症却被开ADs的情况比男性更常见,这可能是治疗过度的迹象。尽管原因尚不清楚,但诊断和治疗指南在这些方面考虑性别差异可能会有所助益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdae/5451647/f0b5be928ba1/146f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdae/5451647/f0b5be928ba1/146f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdae/5451647/f0b5be928ba1/146f1.jpg

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