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脑组织氧化损伤在甲状腺功能减退症相关学习和记忆障碍中的作用

Contribution of Brain Tissue Oxidative Damage in Hypothyroidism-associated Learning and Memory Impairments.

作者信息

Baghcheghi Yousef, Salmani Hossein, Beheshti Farimah, Hosseini Mahmoud

机构信息

Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Adv Biomed Res. 2017 May 22;6:59. doi: 10.4103/2277-9175.206699. eCollection 2017.

Abstract

The brain is a critical target organ for thyroid hormones, and modifications in memory and cognition happen with thyroid dysfunction. The exact mechanisms underlying learning and memory impairments due to hypothyroidism have not been understood yet. Therefore, this review was aimed to compress the results of previous studies which have examined the contribution of brain tissues oxidative damage in hypothyroidism-associated learning and memory impairments.

摘要

大脑是甲状腺激素的关键靶器官,甲状腺功能障碍会导致记忆和认知改变。甲状腺功能减退所致学习和记忆障碍的具体机制尚不清楚。因此,本综述旨在总结以往研究的结果,这些研究探讨了脑组织氧化损伤在甲状腺功能减退相关学习和记忆障碍中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1333/5450450/ebf3318cc4a3/ABR-6-59-g001.jpg

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