Cacucci Francesca, Salinas Patricia, Wills Thomas J
Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.
Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.
Curr Biol. 2017 Jun 5;27(11):R428-R430. doi: 10.1016/j.cub.2017.04.006.
New research reveals that neural activity is required for post-natal maturation of hippocampal neural circuits underlying memory and navigation; this activity-dependent maturation occurs sequentially along the classic 'tri-synaptic' pathway, following the direction of information flow found in the adult hippocampus.
新研究表明,海马体神经回路在出生后的成熟过程中,记忆和导航所依赖的神经活动是必需的;这种依赖活动的成熟沿着经典的“三突触”通路依次发生,其顺序与成年海马体中的信息流方向一致。