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海马体:用于导航的神经回路的活动驱动成熟

Hippocampus: Activity-Driven Maturation of Neural Circuits for Navigation.

作者信息

Cacucci Francesca, Salinas Patricia, Wills Thomas J

机构信息

Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.

Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.

出版信息

Curr Biol. 2017 Jun 5;27(11):R428-R430. doi: 10.1016/j.cub.2017.04.006.

Abstract

New research reveals that neural activity is required for post-natal maturation of hippocampal neural circuits underlying memory and navigation; this activity-dependent maturation occurs sequentially along the classic 'tri-synaptic' pathway, following the direction of information flow found in the adult hippocampus.

摘要

新研究表明,海马体神经回路在出生后的成熟过程中,记忆和导航所依赖的神经活动是必需的;这种依赖活动的成熟沿着经典的“三突触”通路依次发生,其顺序与成年海马体中的信息流方向一致。

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