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宝石光谱CT在颈动脉粥样硬化诊断中的临床相关性

Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis.

作者信息

Wang Jing-Jian, Fan Shu-Jie, Wang Long-Long, Gao Yan-Zhong, Liu Xiao-Juan

机构信息

The First Imaging Department, The Ninth Hospital of Xi'an, Xi'an, Shaanxi 710054, P.R. China.

The Fifth Department, Xi'an Mental Health Center, Xi'an, Shaanxi 710061, P.R. China.

出版信息

Exp Ther Med. 2017 Jun;13(6):2629-2636. doi: 10.3892/etm.2017.4342. Epub 2017 Apr 13.

Abstract

A variety of imaging methods can be used in the diagnosis of atherosclerotic plaques. In the present study, we investigated the morphology and composition of atherosclerotic plaque associated with ischemic cerebral infarction by comparing gemstone spectral computed tomography (GSCT) and traditional multi-slice CT (MSCT). In total, 200 patients were enrolled and divided into the experimental group (n=100), which underwent GSCT, and the control group (n=100), which underwent MSCT. All the cases were followed up to observe disease outcomes in patients with different atherosclerotic plaque types, and adverse events in carotid artery stenosis or cerebral infarction were recorded. Compared with traditional MSCT, sensitivity (93.2%), specificity (84.5%), and accuracy (91.0%) of GSCT were significantly higher. We found a correlation between vulnerable plaque of carotid atherosclerotic plaque and the occurrence of cerebral infarction. These results suggest the advantages of GSCT in analyzing atherosclerotic plaque and predicting the risk of ischemic cerebral infarction.

摘要

多种成像方法可用于诊断动脉粥样硬化斑块。在本研究中,我们通过比较宝石光谱计算机断层扫描(GSCT)和传统多层螺旋CT(MSCT),研究了与缺血性脑梗死相关的动脉粥样硬化斑块的形态和成分。总共纳入了200例患者,分为接受GSCT的实验组(n = 100)和接受MSCT的对照组(n = 100)。对所有病例进行随访,观察不同动脉粥样硬化斑块类型患者的疾病转归,并记录颈动脉狭窄或脑梗死的不良事件。与传统MSCT相比,GSCT的敏感性(93.2%)、特异性(84.5%)和准确性(91.0%)显著更高。我们发现颈动脉粥样硬化斑块的易损斑块与脑梗死的发生之间存在相关性。这些结果表明GSCT在分析动脉粥样硬化斑块和预测缺血性脑梗死风险方面的优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/291d/5450728/76c3e29780ab/etm-13-06-2629-g00.jpg

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