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急诊科单纯性尿路感染:对当地实践模式的回顾。

Uncomplicated urinary tract infections in the emergency department: a review of local practice patterns.

机构信息

*Department of Family & Community Medicine,University of Toronto,Toronto,ON.

出版信息

CJEM. 2018 Jul;20(4):572-577. doi: 10.1017/cem.2017.39. Epub 2017 Jun 7.

Abstract

OBJECTIVES

To determine the number of urine cultures ordered for women who presented to the emergency department (ED) with symptoms of uncomplicated UTI, and whether a culture result impacted subsequent management.

METHODS

This was a retrospective chart review of non-pregnant women aged 18-39 presenting to one of two academic EDs with a discharge diagnosis of uncomplicated UTI over a one-year study period. Patients were excluded if there was documentation of fever, immunocompromised state, diabetes mellitus, absence of lower urinary tract symptoms, ED administration of intravenous antibiotics, a previous UTI treated with antibiotics in the last 90 days, two weeks post-partum or post-instrumentation.

RESULTS

Of the 512 charts included in the analysis, 494 (96.5%) patients had a urinalysis, of which 463 (93.7%) had positive leukocyte esterase and 90 (18.2%) had positive nitrites. 370 patients (72.3%) had urine cultures performed, of which 236 (63.8%) were positive. 505 (98.6%) patients received antibiotics (53.9% Macrobid; 22.6% Ciprofloxacin; 15.0% Septra; 6.7% other; 1.8% not documented). 7 (1.9%) cultures grew organisms resistant to the prescribed antibiotic; 2 (0.5%) patients received new prescriptions.

CONCLUSIONS

For the majority of young female patients with an uncomplicated UTI, urine cultures did not change management in the ED setting. However, when the diagnosis is uncertain based on symptomology and urinalyses alone, a urine culture may be warranted. Greater efforts should be directed towards educating emergency physicians on accurately diagnosing uncomplicated cystitis and the limited impact of urine cultures on treatment once a diagnosis has been made.

摘要

目的

确定因单纯性尿路感染(UTI)症状就诊于急诊科(ED)的女性所开尿液培养的数量,以及培养结果是否影响后续管理。

方法

这是一项对在一年研究期间因单纯性 UTI 被诊断为非住院患者的 18-39 岁非妊娠女性进行的回顾性图表审查。如果有发热、免疫功能低下、糖尿病、无下尿路感染症状、ED 给予静脉抗生素、过去 90 天内用抗生素治疗过 UTI、产后两周或术后两周的记录,则将患者排除在外。

结果

在纳入分析的 512 份图表中,494 份(96.5%)患者进行了尿液分析,其中 463 份(93.7%)白细胞酯酶阳性,90 份(18.2%)亚硝酸盐阳性。370 名患者(72.3%)进行了尿液培养,其中 236 名(63.8%)为阳性。505 名(98.6%)患者接受了抗生素治疗(53.9%的 Macrobid;22.6%的 Ciprofloxacin;15.0%的 Septra;6.7%的其他药物;1.8%的未记录药物)。7 份(1.9%)培养物中生长的细菌对处方抗生素具有耐药性;2 名(0.5%)患者接受了新处方。

结论

对于大多数患有单纯性 UTI 的年轻女性患者,尿液培养在 ED 环境中并未改变管理。然而,当仅根据症状和尿液分析不能明确诊断时,可能需要进行尿液培养。应更加努力地教育急诊医生准确诊断单纯性膀胱炎,并在做出诊断后了解尿液培养对治疗的影响有限。

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