一例长QT综合征：坎坷之路上的挑战
A case of long QT syndrome: challenges on a bumpy road.
作者信息
Magnusson Peter, Gustafsson Per-Erik
机构信息
Cardiology Research Unit Department of Medicine Karolinska Institutet Stockholm SE-171 76 Sweden.
Centre for Research and Development Uppsala University/Region Gävleborg Gävle SE-801 87 Sweden.
出版信息
Clin Case Rep. 2017 May 4;5(6):954-960. doi: 10.1002/ccr3.985. eCollection 2017 Jun.
Abstract
Beta-agonist treatment during pregnancy may unmask the diagnosis of long QT syndrome. The QT prolongation can result in functional AV block. A history of seizure and/or sudden death in a family member should raise suspicion of ventricular tachycardia. More than one mutation may coexist. Refusal of beta-blocker therapy complicates risk stratification.
摘要
孕期使用β受体激动剂治疗可能会使长QT综合征的诊断更加明显。QT间期延长可导致功能性房室传导阻滞。家族成员中有癫痫和/或猝死病史应引起对室性心动过速的怀疑。可能存在不止一种突变。拒绝β受体阻滞剂治疗会使风险分层变得复杂。
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