Levine Ethan, Rosero Spencer Z, Budzikowski Adam S, Moss Arthur J, Zareba Wojciech, Daubert James P
Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642-8679, USA.
Cleve Clin J Med. 2008 Aug;75(8):591-600. doi: 10.3949/ccjm.75.8.591.
Congenital long QT syndrome is an inherited disorder of cardiac repolarization that predisposes to syncope and to sudden death from polymorphic ventricular tachycardia. The disorder should be suspected when the electrocardiogram shows characteristic QT abnormalities, or when there is a family history of long QT syndrome or of an event that raises suspicion of long QT syndrome, such as sudden death, syncope, or ill-defined "seizure" disorder. We can now classify some types of congenital long QT syndrome according to their genetic mutations and their triggers, such as exercise, rest, or startle.
先天性长QT综合征是一种遗传性心脏复极障碍疾病，易引发晕厥及多形性室性心动过速导致的猝死。当心电图显示特征性QT异常时，或存在长QT综合征家族史，或有引发长QT综合征怀疑的事件（如猝死、晕厥或不明原因的“癫痫”发作）时，应怀疑此病。现在我们可以根据基因突变及其诱因（如运动、休息或惊吓）对某些类型的先天性长QT综合征进行分类。
