Ehouman A, Pinchon M C, Escudier E, Bernaudin J F
Virchows Arch B Cell Pathol Incl Mol Pathol. 1985;48(1):87-95.
Ultrastructural abnormalities of human respiratory tract cilia have been studied in 33 patients: 21 were adults, 18 with chronic bronchitis, and 12 were children, two with situs inversus. Abnormalities, such as the lack of a few dynein arms or the loss of a peripheral doublet were observed quite frequently in both children and adults. However, congenital abnormalities associated with the "immotile cilia syndrome" were rare and were observed in only three of the children and none of the adults.
对33例患者的人类呼吸道纤毛超微结构异常进行了研究:21例为成人,其中18例患有慢性支气管炎;12例为儿童,其中2例脏器反位。在儿童和成人中均相当频繁地观察到一些异常情况,如少数动力蛋白臂缺失或外周双联体丢失。然而,与“不动纤毛综合征”相关的先天性异常很少见,仅在3名儿童中观察到,在成人中未观察到。