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新发短暂性头痛患者头部计算机断层扫描的检出率

Yield of head computed tomography in patients with new onset of transient headaches.

作者信息

Hammond Niamh, Ranta Annemarei

机构信息

Department of Medicine, University of Otago, Wellington, New Zealand.

Department of Neurology, Capital and Coast District Health Board, Wellington, New Zealand.

出版信息

Intern Med J. 2017 Oct;47(10):1141-1146. doi: 10.1111/imj.13517.

Abstract

BACKGROUND

Headache is a common patient complaint. The threshold for brain imaging in headache is debated, especially when the headache is transient, although even if the headache has resolved at presentation, a sentinel bleed heralding a subarachnoid haemorrhage (SAH) often remains a concern.

AIM

To assess the yield of computed tomography (CT) head scan referrals for patients with transient headache symptoms.

METHODS

This study looked at 6 months of CT results in order to assess for brain pathology, with a particular focus on subarachnoid haemorrhage. Where any pathology was identified, detailed chart review looked for potential high-risk indicators.

RESULTS

Between January and July 2015, 531 undifferentiated headache patients were referred for head CT. Of these, 177 (33.3%) presented with a transient or episodic pattern. None of these cases had SAH on imaging nor re-presented with SAH within 3 months of initial CT. However, 7.3% (13/177) had other significant intracranial pathologies. The only significant risk factor for CT abnormality in this setting was focal neurology on presentation (odds ratio 3.1 (95% confidence interval (CI) 1.2-11.0); P = 0.044). All identified cases of SAH over the 6-month study period occurred in patients with persistent headache, and their clinical presentations showed a similar cluster of symptoms to previous literature (including thunderclap headache, vomiting and loss of consciousness).

CONCLUSION

This study suggests that patients with transient headache are at a low risk of SAH; however, further study is needed to quantify this, and other serious pathologies remains a concern, especially in the setting of focal neurology at presentation.

摘要

背景

头痛是患者常见的主诉。头痛患者进行脑部成像检查的阈值存在争议,尤其是当头痛为短暂性时,尽管即便在就诊时头痛已缓解,但蛛网膜下腔出血(SAH)的前驱性出血往往仍令人担忧。

目的

评估因短暂头痛症状转诊的患者进行计算机断层扫描(CT)头部扫描的检出率。

方法

本研究观察了6个月的CT结果以评估脑部病变,特别关注蛛网膜下腔出血。一旦发现任何病变,通过详细的病历回顾寻找潜在的高危指标。

结果

2015年1月至7月期间,531例未分化头痛患者被转诊进行头部CT检查。其中,177例(33.3%)表现为短暂性或发作性模式。这些病例在影像学检查中均未发现SAH,且在首次CT检查后的3个月内也未再次出现SAH。然而,7.3%(13/177)有其他重要的颅内病变。在此情况下,CT异常的唯一重要危险因素是就诊时出现局灶性神经功能缺损(比值比3.1(95%置信区间(CI)1.2 - 11.0);P = 0.044)。在6个月的研究期间,所有确诊的SAH病例均发生在持续性头痛患者中,其临床表现与既往文献报道的症状相似(包括霹雳样头痛、呕吐和意识丧失)。

结论

本研究表明,短暂性头痛患者发生SAH的风险较低;然而,需要进一步研究对此进行量化,且其他严重病变仍令人担忧,尤其是在就诊时出现局灶性神经功能缺损的情况下。

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