Hammond Niamh, Ranta Annemarei
Department of Medicine, University of Otago, Wellington, New Zealand.
Department of Neurology, Capital and Coast District Health Board, Wellington, New Zealand.
Intern Med J. 2017 Oct;47(10):1141-1146. doi: 10.1111/imj.13517.
Headache is a common patient complaint. The threshold for brain imaging in headache is debated, especially when the headache is transient, although even if the headache has resolved at presentation, a sentinel bleed heralding a subarachnoid haemorrhage (SAH) often remains a concern.
To assess the yield of computed tomography (CT) head scan referrals for patients with transient headache symptoms.
This study looked at 6 months of CT results in order to assess for brain pathology, with a particular focus on subarachnoid haemorrhage. Where any pathology was identified, detailed chart review looked for potential high-risk indicators.
Between January and July 2015, 531 undifferentiated headache patients were referred for head CT. Of these, 177 (33.3%) presented with a transient or episodic pattern. None of these cases had SAH on imaging nor re-presented with SAH within 3 months of initial CT. However, 7.3% (13/177) had other significant intracranial pathologies. The only significant risk factor for CT abnormality in this setting was focal neurology on presentation (odds ratio 3.1 (95% confidence interval (CI) 1.2-11.0); P = 0.044). All identified cases of SAH over the 6-month study period occurred in patients with persistent headache, and their clinical presentations showed a similar cluster of symptoms to previous literature (including thunderclap headache, vomiting and loss of consciousness).
This study suggests that patients with transient headache are at a low risk of SAH; however, further study is needed to quantify this, and other serious pathologies remains a concern, especially in the setting of focal neurology at presentation.
头痛是患者常见的主诉。头痛患者进行脑部成像检查的阈值存在争议,尤其是当头痛为短暂性时,尽管即便在就诊时头痛已缓解,但蛛网膜下腔出血(SAH)的前驱性出血往往仍令人担忧。
评估因短暂头痛症状转诊的患者进行计算机断层扫描(CT)头部扫描的检出率。
本研究观察了6个月的CT结果以评估脑部病变,特别关注蛛网膜下腔出血。一旦发现任何病变,通过详细的病历回顾寻找潜在的高危指标。
2015年1月至7月期间,531例未分化头痛患者被转诊进行头部CT检查。其中,177例(33.3%)表现为短暂性或发作性模式。这些病例在影像学检查中均未发现SAH,且在首次CT检查后的3个月内也未再次出现SAH。然而,7.3%(13/177)有其他重要的颅内病变。在此情况下,CT异常的唯一重要危险因素是就诊时出现局灶性神经功能缺损(比值比3.1(95%置信区间(CI)1.2 - 11.0);P = 0.044)。在6个月的研究期间,所有确诊的SAH病例均发生在持续性头痛患者中,其临床表现与既往文献报道的症状相似(包括霹雳样头痛、呕吐和意识丧失)。
本研究表明,短暂性头痛患者发生SAH的风险较低;然而,需要进一步研究对此进行量化,且其他严重病变仍令人担忧,尤其是在就诊时出现局灶性神经功能缺损的情况下。