Nanji Afshan A, Mercado Carolina, Galor Anat, Dubovy Sander, Karp Carol L
Int Ophthalmol Clin. 2017 Summer;57(3):47-62. doi: 10.1097/IIO.0000000000000174.
To evaluate technologies and techniques available for the diagnosis of ocular surface tumors.
A review of the literature from 1947 to 2017, through the PubMed Database, was conducted in order to evaluate current diagnostic methods for ocular surface tumors.
Ocular surface squamous neoplasia, conjunctival melanoma, and conjunctival lymphoma are the three most common ocular surface malignancies. Technologies available to assist with diagnosis of these conditions, in addition to full thickness biopsy, include vital dyes, aspiration and impression cytology, in vivo confocal microscopy, ultrasound biomicroscopy, genetic testing, and anterior segment optical coherence tomography.
Histology remains the gold standard for diagnosis for all 3 of these malignancies. However, multiple diagnostic techniques are available to assist in making preliminary and early diagnoses, in differentiating between similar-appearing lesions, and in some cases, avoiding biopsy prior to initiating treatment. As imaging and technology continue to evolve, these adjunctive techniques will likely continue to play a greater role in clinical practice.
评估可用于诊断眼表肿瘤的技术和方法。
通过PubMed数据库对1947年至2017年的文献进行综述，以评估当前眼表肿瘤的诊断方法。
眼表鳞状上皮瘤、结膜黑色素瘤和结膜淋巴瘤是三种最常见的眼表恶性肿瘤。除全层活检外，可用于辅助诊断这些病症的技术包括活性染料、抽吸和印片细胞学检查、活体共聚焦显微镜检查、超声生物显微镜检查、基因检测以及眼前节光学相干断层扫描。
组织学仍然是这三种恶性肿瘤诊断的金标准。然而，有多种诊断技术可辅助进行初步和早期诊断，区分外观相似的病变，并且在某些情况下，在开始治疗前避免活检。随着成像和技术不断发展，这些辅助技术可能会在临床实践中继续发挥更大作用。
