Department of Stereotactic Neurosurgery, University Hospital Magdeburg, Leipziger Strasse 44, 39120, Magdeburg, Germany.
Department of Neurosurgery, Faculty of Medicine and University Hospital Carl Gustav Carus, Technical University Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
J Neural Transm (Vienna). 2017 Sep;124(9):1093-1096. doi: 10.1007/s00702-017-1741-8. Epub 2017 Jun 7.
The purpose of this study was to assess the influence of age on thalamic deep brain stimulation (DBS) in essential tremor (ET). Tremor, cognition, mood and adverse events in patients with thalamic DBS for ET were evaluated in 26 consecutive patients with established standardized methods for tremor and cognition. Twelve patients <70 and 14 patients ≥70 years were included and followed for 2 years. Clinical outcomes did not differ significantly. DBS seems to be safe and effective for ET independent of age.
本研究旨在评估年龄对丘脑深部脑刺激(DBS)治疗原发性震颤(ET)的影响。通过对震颤和认知的标准化评估方法,对 26 例接受丘脑 DBS 治疗的 ET 患者的震颤、认知、情绪和不良事件进行评估。纳入的患者包括 12 名<70 岁和 14 名≥70 岁的患者,随访 2 年。临床结果无显著差异。DBS 似乎对 ET 安全有效,与年龄无关。