Hovens J G F M, Giltay E J, van Hemert A M, Penninx B W J H
Tijdschr Psychiatr. 2017;59(5):286-296.
Childhood trauma and negative life events in childhood are risk factors for the development of anxiety and depressive disorders in adulthood.
AIM: To increase our understanding of the specific associations between trauma and negative life events in childhood and the development and course of anxiety and depressive disorders in adulthood.
METHOD: Our research findings are based on data from the Netherlands Study of Depression and Anxiety (NESDA). In our article we report on two cross-sectional and three prospective studies.
RESULTS: All domains of childhood trauma are risk factors for the development of anxiety and/or depressive disorders in adulthood. Emotional neglect is the main independent predictor of the occurrence and the course of anxiety and depressive disorders. Certain personality characteristics and more unfavorable clinical factors play an important role in mediating the relationship between childhood trauma and the course of anxiety and depressive disorders later in life.
CONCLUSION: Not only does childhood trauma increase an individual's vulnerability to the development of anxiety and depressive disorders, it is also associated with a more serious and more chronic course of these disorders. Our studies have provided new insights into the underlying mechanism that links childhood trauma and anxiety and later anxiety depressive disorders. Consequently, we feel justified in making some recommendations with regards to clinical practice and public health interventions.
童年创伤和童年时期的负面生活事件是成年后患焦虑症和抑郁症的风险因素。
加深我们对童年创伤与负面生活事件之间的具体关联,以及它们与成年后焦虑症和抑郁症的发生及病程之间关系的理解。
我们的研究结果基于荷兰抑郁症和焦虑症研究(NESDA)的数据。在本文中,我们报告了两项横断面研究和三项前瞻性研究。
童年创伤的所有领域都是成年后患焦虑症和/或抑郁症的风险因素。情感忽视是焦虑症和抑郁症发生及病程的主要独立预测因素。某些人格特征和更不利的临床因素在介导童年创伤与晚年焦虑症和抑郁症病程之间的关系中起重要作用。
童年创伤不仅会增加个体患焦虑症和抑郁症的易感性,还与这些疾病更严重、更慢性的病程相关。我们的研究为连接童年创伤与焦虑症以及后来的焦虑抑郁症的潜在机制提供了新的见解。因此,我们认为有理由就临床实践和公共卫生干预提出一些建议。