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氰基丙烯酸正丁酯用于创伤及其他病症后颅骨固定的疗效与安全性

Efficacy and Safety of Using N-Butyl Cyanoacrylate in Cranial Fixation Following Trauma and Other Pathologies.

作者信息

Sultan Ahmed, Mohamed Abbas

机构信息

Alexandria University, Department of Neurosurgery, Alexandria, Egypt.

出版信息

Turk Neurosurg. 2018;28(3):416-420. doi: 10.5137/1019-5149.JTN.20117-17.1.

Abstract

AIM

Skull bone fixation following different cranial surgeries is essential and should be rigid, simple and cheap. We describe our technique of cranial fixation using the adhesive cyanoacrylates.

MATERIAL AND METHODS

At the end of cranial and intracranial surgeries the craniotomy flap and bone pieces are returned, realigned and fixed using HistoacrylŽ (N-Butyl Cyanoacrylate) glue. The glue is applied all around the flap in 360-degree fashion.

RESULTS

The adhesive material was used in 24 cases after different surgeries involving the calvaria of the skull. Patient age ranged from 1 month to 55 years. Seven cases presented with depressed fractures, 5 traumatic hematomas, and 2 cases after decompressive craniotomies for malignant middle cerebral artery (MCA) infarctions, and 10 cases operated for brain tumors. No skin or bone flap infections were encountered during the follow up period and fusion of the edges of bone flap was observed on follow-up imaging in most of the cases.

CONCLUSION

Skull bone realignment and fixation using glue is a simple, safe, and inexpensive method. The operative procedure was not prolonged. Good cosmetic appearance and realignment and fusion of the bone flap were achieved. Further neuroimaging methods are not prohibited. Glue is suitable for the growing skull of children. Glue is also suitable in compound depressed fractures of the skull with possibility of infection.

摘要

目的

不同颅脑手术后颅骨固定至关重要,且应坚固、简便且成本低廉。我们描述了使用氰基丙烯酸酯粘合剂进行颅骨固定的技术。

材料与方法

在颅脑和颅内手术结束时,将颅骨切开瓣和骨块复位、重新对齐并用Histoacryl®(正丁基氰基丙烯酸酯)胶水固定。胶水以360度方式涂抹在瓣片周围。

结果

在涉及颅骨顶骨的不同手术后,有24例使用了这种粘合材料。患者年龄从1个月至55岁不等。7例为凹陷性骨折,5例为创伤性血肿,2例为恶性大脑中动脉(MCA)梗死减压开颅术后,10例为脑肿瘤手术。随访期间未遇到皮肤或骨瓣感染,大多数病例在随访影像学检查中观察到骨瓣边缘融合。

结论

使用胶水进行颅骨重新对齐和固定是一种简单、安全且廉价的方法。手术过程未延长。实现了良好的外观以及骨瓣的重新对齐和融合。不影响进一步的神经影像学检查方法。胶水适用于儿童正在生长的颅骨。胶水也适用于可能发生感染的颅骨复合凹陷性骨折。

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