Section of Occupational Medicine, Institute of Public Health, Catholic University of Sacred Heart, Rome (Dr Fontana, Dr Capitanelli); Department of Community Health Systems, University of California San Francisco, San Francisco, California (Dr Lee); Unit of Pneumology, Department of Internal Medicine, Hospital of Vittorio Veneto, Vittorio Veneto (Dr Re); Laboratory of Respiratory Inflammation, IRCCS Istituti Clinici Scientifici Maugeri, Telese Terme, Benevento (Dr Maniscalco); Section of Occupational Medicine, Department of Public Health, University of Naples "Federico II", Naples (Dr Mauriello, Dr Iavicoli), Italy.
J Occup Environ Med. 2017 Aug;59(8):775-788. doi: 10.1097/JOM.0000000000001072.
Chronic obstructive pulmonary disease (COPD) is a significant public health problem but it is unclear whether agricultural work causes an increased risk of disease. The aim of this review was to study COPD risk among farmers and analyze occupational exposures in agricultural workplaces.
A systematic literature search was conducted to identify epidemiological studies investigating COPD prevalence in farmers.
In the 14 studies reviewed, COPD prevalence ranged from 3% to 68% due to different characteristics of study population, working activities, case definition/diagnosis. Livestock farmers were at higher risk and significant associations were observed for exposure to organic dusts, endotoxins, mites, ammonia, and hydrogen sulfide.
Farming work was associated with greater risk of developing COPD. However, considering the several variables that may influence the disease prevalence in farmers, we suggest the adoption of a standardized research strategy.
慢性阻塞性肺疾病(COPD)是一个重大的公共卫生问题,但目前尚不清楚农业工作是否会增加患病风险。本综述的目的是研究农民患 COPD 的风险,并分析农业工作场所的职业暴露情况。
系统地检索了调查农民 COPD 患病率的流行病学研究。
在综述的 14 项研究中,由于研究人群、工作活动、病例定义/诊断的不同特征,COPD 的患病率从 3%到 68%不等。饲养牲畜的农民患病风险更高,并且与接触有机粉尘、内毒素、螨虫、氨和硫化氢显著相关。
农业工作与患 COPD 的风险增加有关。然而,考虑到可能影响农民中疾病流行的几个变量,我们建议采用标准化的研究策略。