Sasson Evan, James Marian, Wubshet Berhane, Todorov Darko, Cohen Henry
Consult Pharm. 2017 Jun 1;32(6):352-359. doi: 10.4140/TCP.n.2017.352.
Evaluate whether implementing of pharmacy-led psychopharmacology rounds in a nursing facility will improve the rate of antipsychotic use.
Single-center, prospective; medication use evaluation (MUE).
Rutland Nursing Home, Brooklyn, New York.
Nursing facility residents, excluding the pediatric unit.
Weekly interdisciplinary psychopharmacology rounds that include: clinical pharmacists, nurse managers, medical director, social workers, and administration. Antipsychotics were analyzed for all residents for appropriateness of use, proper documentation, and adequate monitoring.
Assess the overall rate of reduction of antipsychotic use after implementation of psychopharmacology rounds. Secondary outcomes assessed improvements in monitoring and documentation for residents on antipsychotics.
A total of 81 residents were evaluated over the six-month MUE. Of those residents, 20 had their antipsychotics discontinued, and 11 had their antipsychotics tapered. The overall use of antipsychotics decreased from 14.6% (62/422) to 12.2% (50/411) (P = 0.285). Compliance with indications generally approved by the Centers for Medicare & Medicaid Services improved from 65% (37/57) to 85% (46/54) (P = 0.008). Matching indications on the psychiatry consult and the medication order improved from 58% (33/57) to 80% (43/54) (P = 0.015). Metabolic laboratory monitoring improved from 58% (33/57) to 83% (45/54) (P = 0.003). Improvements in timeliness of psychiatry and ophthalmology consults were not statistically significant.
Implementing interdisciplinary psycho-pharmacology rounds in a nursing facility resulted in a reduction of inappropriate antipsychotic use and improved monitoring and documentation.
评估在一家护理机构实施由药剂师主导的精神药理学查房是否会提高抗精神病药物的使用比例。
单中心、前瞻性;药物使用评估(MUE)。
纽约布鲁克林的拉特兰疗养院。
护理机构的居民,儿科病房除外。
每周进行跨学科精神药理学查房,参与人员包括:临床药剂师、护士长、医疗主任、社会工作者和管理人员。对所有居民的抗精神病药物进行分析,评估其使用的合理性、文件记录的准确性以及监测的充分性。
评估精神药理学查房实施后抗精神病药物使用的总体减少率。次要结局指标评估抗精神病药物使用者在监测和文件记录方面的改善情况。
在为期6个月的药物使用评估期间,共评估了81名居民。其中,20名居民停用了抗精神病药物,11名居民减少了抗精神病药物的用量。抗精神病药物的总体使用率从14.6%(62/422)降至12.2%(50/411)(P = 0.285)。符合医疗保险和医疗补助服务中心普遍认可的适应症的比例从65%(37/57)提高到85%(46/54)(P = 0.008)。精神科会诊与用药医嘱上适应症的匹配度从58%(33/57)提高到80%(43/54)(P = 0.015)。代谢实验室监测从58%(33/57)提高到83%(45/54)(P = 0.003)。精神科和眼科会诊及时性的改善无统计学意义。
在护理机构实施跨学科精神药理学查房可减少抗精神病药物的不当使用,并改善监测和文件记录情况。