一种用于研究小鼠乳腺肿瘤病毒的新细胞系统。
A new cell system for the study of mouse mammary tumour virus.
作者信息
Litvinov S V, Sokova O I, Kryukova I N
出版信息
Acta Virol. 1985 Jan;29(1):83-6.
PMID:2859767
Abstract
A stable cell line derived from mammary gland cancer of Djungarian hamster is proposed for the study of oncogenic properties of mouse mammary tumour virus (MMTV). The conditions of infection and expression of the viral genome in this cell line are described in addition to the chromosomal composition or the original and infected cells. The MMTV-infected cells showed increased colony formation in semi-solid media. The advantages of the new cell system are discussed.
摘要
本文提出了一种源自黑线仓鼠乳腺癌的稳定细胞系，用于研究小鼠乳腺肿瘤病毒（MMTV）的致癌特性。除了原始细胞和感染细胞的染色体组成外，还描述了该细胞系中病毒基因组的感染条件和表达情况。MMTV感染的细胞在半固体培养基中显示出集落形成增加。讨论了新细胞系统的优点。
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