Giordano Mauro, Ciarambino Tiziana, Priore Emanuela Lo, Castellino Pietro, Malatino Lorenzo, Cataliotti Alessandro, Paolisso Giuseppe, Adinolfi Luigi Elio
Department of Medical, Surgical, Neurological, Metabolic and Geriatrics Sciences, University of Campania "L. Vanvitelli", Italy.
Department of Medical, Surgical, Neurological, Metabolic and Geriatrics Sciences, University of Campania "L. Vanvitelli", Italy.
Am J Emerg Med. 2017 Nov;35(11):1691-1694. doi: 10.1016/j.ajem.2017.05.050. Epub 2017 May 31.
We investigated the serum sodium correction rate on length of hospitalization and survival rate, in severe chronic hyponatremic patients at the Emergency Department (ED).
An observational study using clinical chart review.
The ED of the University Hospital of Marcianise, Caserta, Italy with approximately 30,000 patients visits a year.
We reviewed sixty-seven patients with severe hyponatremia subdivided in 2 subgroups: group A consisting of 35 patients with serum sodium correction rate<0.3mmol/h and group B consisting of 32 patients with serum sodium correction rate between <0.5 and ≥0.3mmol/h.
Emergency patients were evaluated for serum sodium correction rate for hyponatremia by clinical chart review.
Severe hyponatremia was defined as a serum sodium level<120mmol/l. Mean serum sodium correction rate of hyponatremia was of 0.17±0.09% in group A and 0.41±0.05% in group B (p<0.001 vs group A). The length of hospital stay was 10.7±3.7days for group A, and it was significantly decreased to 3.8±0.4days for group B (p<0.005 vs group A). In addition we observed that correction rate of hyponatremia in group A was associated with a significantly lower survival rate (25%) in comparison to group B (60%) (p<0.001 vs group A).
We observed that serum sodium correction rate ≥0.3 and <0.5mmol/h was associated with a shorter length of hospital stay and a major survival rate.
我们调查了急诊科严重慢性低钠血症患者的血清钠纠正率对住院时间和生存率的影响。
一项采用临床病历回顾的观察性研究。
意大利卡塞塔马尔恰尼塞大学医院急诊科，每年约有30000人次就诊。
我们回顾了67例严重低钠血症患者，分为2个亚组：A组由35例血清钠纠正率<0.3mmol/h的患者组成，B组由32例血清钠纠正率在<0.5至≥0.3mmol/h之间的患者组成。
通过临床病历回顾对急诊患者的低钠血症血清钠纠正率进行评估。
严重低钠血症定义为血清钠水平<120mmol/l。A组低钠血症的平均血清钠纠正率为0.17±0.09%，B组为0.41±0.05%（与A组相比，p<0.001）。A组的住院时间为10.7±3.7天，B组显著缩短至3.8±0.4天（与A组相比，p<0.005）。此外，我们观察到，与B组（60%）相比，A组低钠血症的纠正率与显著较低的生存率（25%）相关（与A组相比，p<0.001）。
我们观察到血清钠纠正率≥0.3且<0.5mmol/h与较短的住院时间和较高的生存率相关。
