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厄瓜多尔加拉帕戈斯群岛伊莎贝拉岛的高血糖和血脂异常:一个孤立岛屿社区心血管危险因素的初步研究。

Hyperglycemia and dyslipidemia of Isabela, Galápagos, Ecuador: A pilot study of cardiovascular risk factors in an Isolated Island community.

作者信息

Alexander Abigail, Florez Hermes, Ladera Nuria

机构信息

University of Miami Miller School of Medicine, USA; International Outreach Initiative, Galápagos, Ecuador.

University of Miami Miller School of Medicine, USA.

出版信息

Diabetes Res Clin Pract. 2017 Aug;130:108-112. doi: 10.1016/j.diabres.2017.05.015. Epub 2017 May 26.

DOI:10.1016/j.diabres.2017.05.015
PMID:28601002
Abstract

AIM

To evaluate the prevalence of hyperglycemia and dyslipidemia in the population of Isabela, Galápagos, Ecuador, across gender and age (above or below 50).

METHODS

In this population-based retrospective cross-sectional study among individuals in Isabela, Galápagos, Ecuador, demographic and metabolic factors were evaluated based on World Health Organization (WHO) Global Guidelines.

RESULTS

The population overall exceeded the WHO guidelines for cardiovascular health. As to be expected, there was significance in the trend of increasing dyslipidemia and hyperglycemia with age except postprandial glucose. In those individuals below the age of 50, 8.0%, 49% and 26% had hyperglycemia, hypercholesterolemia and hypertriglyceridemia, respectively. However, in those above 50, they measured 24%, 68% and 36% respectively, showing a significant increase.

CONCLUSIONS

Hyperglycemia and dyslipidemia appear to be prevalent in Isabela, Galápagos, Ecuador and this pilot study supports further research into metabolic syndrome and diabetes. Such data may help in healthcare planning and screening to ensure not only timely diagnosis, but prevention. The limitations of this data illustrate modalities that data collection can be improved, such as having a linked clinical history to the data itself and better patient follow up for such entities as post prandial glucose, for example. However, this pilot study presents a starting point for future directions of research, such as ascertaining prevalence of diabetes type II, metabolic syndrome and cardiovascular disease.

摘要

目的

评估厄瓜多尔加拉帕戈斯群岛伊莎贝拉岛人群中高血糖和血脂异常在不同性别和年龄(50岁及以上或以下)的患病率。

方法

在厄瓜多尔加拉帕戈斯群岛伊莎贝拉岛人群中开展的这项基于人群的回顾性横断面研究中,根据世界卫生组织(WHO)全球指南对人口统计学和代谢因素进行了评估。

结果

总体人群超出了WHO心血管健康指南标准。不出所料,除餐后血糖外,血脂异常和高血糖患病率随年龄增长呈上升趋势,差异具有统计学意义。在50岁以下的个体中,高血糖、高胆固醇血症和高甘油三酯血症的患病率分别为8.0%、49%和26%。然而,在50岁以上的个体中,这些患病率分别为24%、68%和36%,呈现出显著上升。

结论

高血糖和血脂异常在厄瓜多尔加拉帕戈斯群岛伊莎贝拉岛似乎普遍存在,这项初步研究支持对代谢综合征和糖尿病进行进一步研究。此类数据可能有助于医疗保健规划和筛查,以确保不仅能及时诊断,还能进行预防。这些数据的局限性说明了可以改进数据收集的方式,例如将临床病史与数据本身相联系,以及对餐后血糖等指标进行更好的患者随访。然而,这项初步研究为未来的研究方向提供了一个起点,例如确定2型糖尿病、代谢综合征和心血管疾病的患病率。

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