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塞内加尔成年人群中的血脂异常、肥胖及其他心血管危险因素。

Dyslipidemia, obesity and other cardiovascular risk factors in the adult population in Senegal.

作者信息

Doupa Dominique, Seck Sidy Mohamed, Dia Charles Abdou, Diallo Fatou Agne, Kane Modou Oumy, Kane Adama, Gueye Pape Madieye, Mbaye Maimouna Ndour, Gueye Lamine, Jobe Modou

机构信息

Laboratoire de Biochimie-Biologie Moléculaire, Unités de Formation et de Recherche (UFR), Santé Université Gaston Berger de Saint-Louis, Sénégal.

Service de Néphrologie, Unités de Formation et de Recherche (UFR), Santé Université Gaston Berger de Saint-Louis, Sénégal.

出版信息

Pan Afr Med J. 2014 Oct 21;19:181. doi: 10.11604/pamj.2014.19.181.4872. eCollection 2014.

Abstract

INTRODUCTION

According to the WHO, 50% of deaths worldwide (40.1% in developing countries) are due to chronic non-communicable diseases (NCDs). Of these chronic NCDs, cardiovascular diseases remain the leading cause of death and disability in developed countries. The Framingham study has shown the importance of hypercholesterolemia as a primary risk factor. In Senegal, the epidemiology of dyslipidemia and obesity are still poorly understood due to the lack of comprehensive studies on their impact on the general population. This motivated this study to look into the key epidemiologic and socio-demographic determinants of these risk factors.

METHODS

It was a cross-sectional descriptive epidemiological survey which included 1037 individuals selected by cluster sampling. Data were collected using a questionnaire following the WHO STEPwise approach. Socio-demographic, health and biomedical variables were collected. P value <0.05 was considered to be statistically significant.

RESULTS

The average age was 48 years with a female predominance (M: F of 0.6). The literacy rate was 65.2% and 44.7% of participants were from rural areas. The prevalence of hypercholesterolemia, hyperLDLemia, hypoHDLemia, hypertriglyceridemia and mixed hyperlipidemia were 56%, 22.5%, 12.4%, 7.11% and 1.9% respectively. One in four was obese (BMI> 30kg/m2) and 34.8% had abdominal obesity. The main factors significantly associated with dyslipidemia were obesity, urban dwelling, physical inactivity and a family history of dyslipidemia.

CONCLUSION

The prevalence of dyslipidemia, obesity and other risk factors in the population was high needing immediate care for those affected and implementation of prevention strategies.

摘要

引言

据世界卫生组织称,全球50%的死亡(发展中国家为40.1%)归因于慢性非传染性疾病(NCDs)。在这些慢性非传染性疾病中,心血管疾病仍然是发达国家死亡和残疾的主要原因。弗雷明汉姆研究表明高胆固醇血症作为主要危险因素的重要性。在塞内加尔,由于缺乏关于血脂异常和肥胖对普通人群影响的全面研究,对它们的流行病学情况仍知之甚少。这促使本研究探究这些危险因素的关键流行病学和社会人口学决定因素。

方法

这是一项横断面描述性流行病学调查,通过整群抽样选取了1037名个体。采用世界卫生组织的逐步调查方法,通过问卷收集数据。收集了社会人口学、健康和生物医学变量。P值<0.05被认为具有统计学意义。

结果

平均年龄为48岁,女性占主导(男:女为0.6)。识字率为65.2%,44.7%的参与者来自农村地区。高胆固醇血症、高LDL血症、低HDL血症、高甘油三酯血症和混合性高脂血症的患病率分别为56%、22.5%、12.4%、7.11%和1.9%。四分之一的人肥胖(BMI>30kg/m²),34.8%的人有腹型肥胖。与血脂异常显著相关的主要因素是肥胖、城市居住、缺乏身体活动和血脂异常家族史。

结论

人群中血脂异常、肥胖和其他危险因素的患病率很高,需要立即对受影响者进行治疗并实施预防策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e07e/4366126/5ccad24a07ad/PAMJ-19-181-g001.jpg

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