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中年期的中毒性“发作期”意识模糊:苯二氮䓬类药物治疗

Toxic "ictal" confusion in middle age: treatment with benzodiazepines.

作者信息

Van Sweden B

出版信息

J Neurol Neurosurg Psychiatry. 1985 May;48(5):472-6. doi: 10.1136/jnnp.48.5.472.

Abstract

In adult and elderly non-epileptic subjects psychoactive drugs may cause an altered state of consciousness and repetitive irritative EEG discharges. The neurotoxic pathogenesis of this drug-induced confusion and the differentiation from absence status are discussed. Dramatic relief by intravenous benzodiazepines is detailed. Recovery is complete and prognosis is excellent on withdrawal of the offending drug.

摘要

在成年和老年非癫痫患者中,精神活性药物可能会导致意识状态改变和脑电图反复出现刺激性放电。本文讨论了这种药物引起的意识模糊的神经毒性发病机制以及与失神状态的鉴别。详细介绍了静脉注射苯二氮䓬类药物后的显著缓解情况。停用相关药物后可完全康复,预后良好。

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引用本文的文献

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Drug-induced delirium. Incidence, management and prevention.药物性谵妄。发病率、管理与预防。
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本文引用的文献

2
[Myoclonus of toxic origin].[中毒性肌阵挛]
Rev Electroencephalogr Neurophysiol Clin. 1982 Nov;12(3):210-8. doi: 10.1016/s0370-4475(82)80046-4.
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Adult onset absence status: a report of six cases.成人起病失神状态:6例报告
Clin Electroencephalogr. 1981 Oct;12(4):199-204. doi: 10.1177/155005948101200406.
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Ann Intern Med. 1968 Jun;68(6):1271-9. doi: 10.7326/0003-4819-68-6-1271.

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