中年期的中毒性“发作期”意识模糊：苯二氮䓬类药物治疗
Toxic "ictal" confusion in middle age: treatment with benzodiazepines.
作者信息
Van Sweden B
出版信息
J Neurol Neurosurg Psychiatry. 1985 May;48(5):472-6. doi: 10.1136/jnnp.48.5.472.
Abstract
In adult and elderly non-epileptic subjects psychoactive drugs may cause an altered state of consciousness and repetitive irritative EEG discharges. The neurotoxic pathogenesis of this drug-induced confusion and the differentiation from absence status are discussed. Dramatic relief by intravenous benzodiazepines is detailed. Recovery is complete and prognosis is excellent on withdrawal of the offending drug.
摘要
在成年和老年非癫痫患者中，精神活性药物可能会导致意识状态改变和脑电图反复出现刺激性放电。本文讨论了这种药物引起的意识模糊的神经毒性发病机制以及与失神状态的鉴别。详细介绍了静脉注射苯二氮䓬类药物后的显著缓解情况。停用相关药物后可完全康复，预后良好。
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本文引用的文献
1
THE SIGNIFICANCE OF PERIODIC LATERALIZED EPILEPTIFORM DISCHARGES IN EEG: AN ELECTROGRAPHIC, CLINICAL AND PATHOLOGICAL STUDY.脑电图中周期性一侧性癫痫样放电的意义：一项脑电图、临床及病理研究
Electroencephalogr Clin Neurophysiol. 1964 Aug;17:177-93. doi: 10.1016/0013-4694(64)90149-x.
2
[Myoclonus of toxic origin].[中毒性肌阵挛]
Rev Electroencephalogr Neurophysiol Clin. 1982 Nov;12(3):210-8. doi: 10.1016/s0370-4475(82)80046-4.
3
Adult onset absence status: a report of six cases.
Clin Electroencephalogr. 1981 Oct;12(4):199-204. doi: 10.1177/155005948101200406.
4
[Diagnostic value of periodic lateralized complexes in the EEG (author's transl)].
EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1981 Sep;12(3):135-41.
5
[Prolonged confused seizure state of frontal origin in an aged patient].[一位老年患者的额叶起源的持续性意识模糊癫痫状态]
Rev Electroencephalogr Neurophysiol Clin. 1983 Nov;13(2):174-9. doi: 10.1016/s0370-4475(83)80077-x.
6
Periodic EEG discharges in psychiatry.
Eur Neurol. 1983;22(5):359-66. doi: 10.1159/000115583.
7
Neuroleptic-induced seizures. An in vitro technique for assessing relative risk.
Arch Gen Psychiatry. 1982 Feb;39(2):206-9. doi: 10.1001/archpsyc.1982.04290020060011.
8
Neuroleptic neurotoxicity; electro-clinical aspects.抗精神病药神经毒性；电临床方面
Acta Neurol Scand. 1984 Mar;69(3):137-46. doi: 10.1111/j.1600-0404.1984.tb07792.x.
9
10
Petit mal status in adults.成人癫痫小发作持续状态
Ann Intern Med. 1968 Jun;68(6):1271-9. doi: 10.7326/0003-4819-68-6-1271.
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