Lam Phillip H, Taffet George E, Ahmed Ali, Singh Steve
Center for Health and Aging, Veterans Affairs Medical Center, 50 Irving Street NW, Washington, DC 20422, USA; MedStar Heart and Vascular Institute, Georgetown University/MedStar Washington Hospital Center, 110 Irving Street NW, Washington, DC 20010, USA.
Department of Geriatrics and Cardiovascular Medicine, Baylor College of Medicine, 1200 Binz Street, Suite 1470, Houston, TX, 77004, USA.
Heart Fail Clin. 2017 Jul;13(3):581-587. doi: 10.1016/j.hfc.2017.02.011.
Heart failure is a disease of poor prognosis marked by frequent hospitalizations, premature death, and impaired quality of life. Despite advances in medical therapy for patients with heart failure and reduced ejection fraction, mortality and hospitalizations with advanced disease are still increased and the quality of life continues to be poor in this population. The advent of cardiac resynchronization therapy has led to a significant improvement in both survival and symptom management in patients with heart failure and reduced ejection fraction. Its beneficial effects in the elderly population, however, are not well-defined.
心力衰竭是一种预后不良的疾病,其特征为频繁住院、过早死亡和生活质量受损。尽管针对射血分数降低的心力衰竭患者的药物治疗取得了进展,但晚期疾病的死亡率和住院率仍然增加,并且该人群的生活质量仍然很差。心脏再同步治疗的出现已使射血分数降低的心力衰竭患者的生存率和症状管理都有了显著改善。然而,其在老年人群中的有益效果尚不明确。