Datta Subramanya G S, Mehta Ritu, Macha Shrikant, Tripathi Sanjog
Department of Neurosurgery, INHS Asvini, Mumbai, India.
Department of Pathology, INHS Asvini, Mumbai, India.
World Neurosurg. 2017 Sep;105:1037.e1-1037.e7. doi: 10.1016/j.wneu.2017.05.168. Epub 2017 Jul 1.
We describe a series of 3 cases of the rare intramedullary form of primary spinal neurocysticercosis. The cases were seen in varied age groups and showed different profiles at presentation. All the cases were thoroughly evaluated clinically and radiologically. Serologic tests were not conducted. In all cases, magnetic resonance imaging showed a large intramedullary lesion in the thoracic spinal cord consisting of a cystic lesion with a well-defined intramural nodule. One case was managed with steroids and cysticidal therapy, a second case was managed with steroids and surgery (2 emergency procedures), while the third case was managed without any medical or surgical intervention, as the patient was unwilling for either. All cases showed good neurologic recovery. In the second case where surgery was done, histologic examination of the resected specimen demonstrated the cysticercal parasite surrounded by mixed inflammatory infiltrate. As there were no intracranial lesions in all 3 cases, the final diagnosis was primary isolated intramedullary neurocysticercosis. Primary isolated intramedullary-neurocysticercosis remains a rare condition afflicting the spinal cord. It forms a small subset of cysticercal infestation of the neuraxis. Such evidence is rare, and only anecdotal reports are available. Our case series captures the wide spectrum of presentations, as well as the management options, and highlights the varied ways in which these cases were managed.
我们描述了3例罕见的原发性脊髓神经囊尾蚴病髓内型病例。这些病例见于不同年龄组,就诊时表现各异。所有病例均进行了全面的临床和影像学评估。未进行血清学检测。所有病例的磁共振成像均显示胸段脊髓有一个大的髓内病变,由一个有明确壁内结节的囊性病变组成。1例采用类固醇和杀囊治疗,第2例采用类固醇和手术治疗(2次急诊手术),而第3例因患者不愿接受任何一种治疗,未进行任何药物或手术干预。所有病例均显示神经功能恢复良好。在进行手术的第2例中,切除标本的组织学检查显示囊尾蚴寄生虫被混合性炎性浸润包围。由于所有3例均无颅内病变,最终诊断为原发性孤立性髓内神经囊尾蚴病。原发性孤立性髓内神经囊尾蚴病仍然是一种罕见的脊髓疾病。它是神经轴突囊尾蚴感染的一小部分。此类证据很少,仅有一些个案报道。我们的病例系列涵盖了广泛的临床表现以及治疗选择,并突出了这些病例的不同治疗方式。