Seaman F, Shannon I L
J Prosthet Dent. 1979 May;41(5):528-30. doi: 10.1016/0022-3913(79)90086-6.
Effects of various fluoride treatments on the microhardness of human dentin were determined. Treatment with acidulated phosphate-fluoride at pH 3.0 induced a significant (p less than .05) softening when compared to treatment with water. APF at pH 4.0 did not bring about a significant change. Response to treatment with 0.4% SnF2 did not differ significantly from water treatment. Sequential treatment with APF (pH 4.0) followed by SnF2 produced significant (p less than .05) hardening of dentin. This hardening with APF-SnF2 differed at a high level of significance (p less than .001) from the softening produced by the pH 3.0 APF. A similarly significant difference was found between this single APF treatment and the single SnF2 treatment. When hardening of exposed dentin surfaces is desired, the sequential treatment method should be employed.
测定了各种氟化物处理对人牙本质显微硬度的影响。与用水处理相比，用pH值为3.0的酸化磷酸氟处理会导致显著（p<0.05）软化。pH值为4.0的酸化磷酸氟处理未带来显著变化。用0.4%氟化亚锡处理的反应与水处理无显著差异。先用pH值为4.0的酸化磷酸氟处理，再用氟化亚锡处理，会使牙本质产生显著（p<0.05）硬化。这种酸化磷酸氟-氟化亚锡处理产生的硬化与pH值为3.0的酸化磷酸氟产生的软化在高度显著水平（p<0.001）上存在差异。在这种单一的酸化磷酸氟处理和单一的氟化亚锡处理之间也发现了类似的显著差异。当需要使暴露的牙本质表面硬化时，应采用顺序处理方法。
