Ding Xiurong, Yu Yanhua, Chen Ming, Wang Chen, Kang Yanfang, Li Hongman, Lou Jinli
Department of Clinical Laboratory, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, China.
BMC Infect Dis. 2017 Jun 12;17(1):419. doi: 10.1186/s12879-017-2523-5.
Gordonia polyisoprenivorans is a ubiquitous aerobic actinomycetes bacterium that rarely cause infections in humans. Here, we report a case of G. polyisoprenivorans catheter-related bacteremia in an AIDS patient.
A 37-year-old man with a past medical history of AIDS-related lymphoma suffered bacteremia caused by a Gram-positive corynebacterium. The strain was identified as a Gordonia species by matrix-assisted laser desorption ionization-time of flight mass spectrometry and confirmed to G. polyisoprenivorans by 16S rRNA combined with gyrB gene sequencing analyses. The patient was treated with imipenem and had a good outcome.
The findings from our case and previously reported cases indicate that malignant hematologic disease, immunosuppression, and indwelling catheter heighten the risk for G. polyisoprenivorans infection. Molecular methods should be employed for proper identification of G. polyisoprenivorans to the species level.
多食异戊二烯戈登氏菌是一种广泛存在的需氧放线菌，很少引起人类感染。在此，我们报告一例艾滋病患者发生的多食异戊二烯戈登氏菌导管相关菌血症病例。
一名37岁男性，有艾滋病相关淋巴瘤病史，发生了由革兰氏阳性棒状杆菌引起的菌血症。通过基质辅助激光解吸电离飞行时间质谱法将该菌株鉴定为戈登氏菌属，并通过16S rRNA与gyrB基因测序分析确认为多食异戊二烯戈登氏菌。该患者接受亚胺培南治疗，预后良好。
我们病例及先前报道病例的研究结果表明，恶性血液系统疾病、免疫抑制和留置导管会增加多食异戊二烯戈登氏菌感染的风险。应采用分子方法将多食异戊二烯戈登氏菌准确鉴定到种水平。
