Yerevan State Medical University, Yerevan, Armenia.
Trends Pharmacol Sci. 2017 Aug;38(8):667-668. doi: 10.1016/j.tips.2017.05.004. Epub 2017 Jun 9.
Ranibizumab is a humanized, affinity-matured vascular endothelial growth factor (VEGF) antibody fragment that neutralizes all isoforms of VEGF and is FDA approved for use in ophthalmology. Recently it was suggested that ranibizumab may be useful in the treatment of corneal neovascularization, but in reality this therapy is not yet evidence based.
雷珠单抗是一种人源化、亲和力成熟的血管内皮生长因子(VEGF)抗体片段,能中和所有 VEGF 异构体,已获 FDA 批准用于眼科。最近有研究表明,雷珠单抗可能对角膜新生血管的治疗有用,但实际上这种治疗方法还没有循证医学证据。