Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands.
Department of Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
J Am Coll Surg. 2017 Sep;225(3):371-379. doi: 10.1016/j.jamcollsurg.2017.05.016. Epub 2017 Jun 10.
Multiple surgical techniques are recommended to perform cholecystectomy safely in difficult cases, such as conversion to open operation or subtotal cholecystectomy (STC). Reconstituting and fenestrating STC are 2 techniques for STC. The aim of this study was to investigate the short and long-term morbidity and quality of life associated with STC and to compare the outcomes after reconstituting and fenestrating STC.
Patients who underwent STC were identified. Short-term morbidity assessed included bile leakage, bile duct injury, intra-abdominal infection, reinterventions, and readmittance. Long-term morbidity included bile duct stenosis and recurrent biliary events. Differences in the outcomes of fenestrating and reconstituting STC were assessed. Quality of life was assessed by EuroQol 5 Dimensions, Short-Form 36 Questionnaire, and Gastrointestinal Quality of Life Index questionnaires.
Subtotal cholecystectomy was performed in 191 patients, of which 102 (53%) underwent fenestrating STC and 73 (38%) underwent reconstituting STC. Bile leakage was significantly more common after fenestrating STC (18% vs 7%, respectively; p < 0.022). After a median of 6 years follow-up (interquartile range 5 to 10 years), recurrence rate of biliary events was lower after fenestrating than reconstituting STC (9% vs 18%, respectively; p < 0.022). Overall reintervention rate did not differ between the 2 groups: 32% in the fenestrating STC group and 26% in the reconstituting STC group (p = 0.211). Completion cholecystectomy was performed significantly more in patients after fenestrating STC (9% vs 4%; p < 0.022).
Subtotal cholecystectomy is a safe and feasible technique for difficult cases for which conversion only will not solve the difficulty of an inflamed hepatocystic triangle. The choice for reconstituting or fenestrating STC depends on intraoperative conditions and both techniques are associated with specific complications.
对于困难的病例,如转为开腹手术或次全胆囊切除术(STC),有多种手术技术被推荐用于安全地进行胆囊切除术。重建和开窗 STC 是两种 STC 技术。本研究旨在探讨 STC 相关的短期和长期发病率和生活质量,并比较重建和开窗 STC 的结果。
确定了行 STC 的患者。评估的短期发病率包括胆汁漏、胆管损伤、腹腔内感染、再次干预和再次入院。长期发病率包括胆管狭窄和复发性胆道事件。评估了开窗和重建 STC 的结果差异。生活质量通过 EuroQol 5 维度、36 项简短健康调查问卷和胃肠道生活质量指数问卷进行评估。
191 例患者行次全胆囊切除术,其中 102 例(53%)行开窗 STC,73 例(38%)行重建 STC。开窗 STC 后胆汁漏明显更常见(分别为 18%和 7%;p < 0.022)。中位随访 6 年(四分位距 5 至 10 年)后,开窗 STC 后胆道事件复发率低于重建 STC(分别为 9%和 18%;p < 0.022)。两组总体再干预率无差异:开窗 STC 组为 32%,重建 STC 组为 26%(p = 0.211)。在开窗 STC 后完成胆囊切除术的患者明显更多(分别为 9%和 4%;p < 0.022)。
对于困难的病例,次全胆囊切除术是一种安全可行的技术,对于炎症性胆囊三角难以处理的病例,仅转为开腹手术并不能解决问题。选择重建或开窗 STC 取决于术中情况,两种技术都与特定的并发症相关。