Wong P T, Leong S F
Ann Acad Med Singap. 1985 Jan;14(1):143-6.
At 10 mM (unless stated), GABA (5 mM), glycine and hydroxyproline inhibited delta 1-pyrroline-5-carboxylate dehydrogenase by 84, 85 and 76%, respectively. Glutamate, glutamine, proline, cysteine and alanine inhibited delta 1-pyrroline-5-carboxylate dehydrogenase by 41-59%. Other amino acids studied were either ineffective or marginally effective. It is concluded that delta 1-pyrroline-5-carboxylate dehydrogenase may be a regulatory enzyme in the ornithine-glutamate pathway.
在10 mM（除非另有说明）时，γ-氨基丁酸（5 mM）、甘氨酸和羟脯氨酸分别抑制δ1-吡咯啉-5-羧酸脱氢酶84%、85%和76%。谷氨酸、谷氨酰胺、脯氨酸、半胱氨酸和丙氨酸抑制δ1-吡咯啉-5-羧酸脱氢酶41%-59%。所研究的其他氨基酸要么无效，要么效果甚微。得出的结论是，δ1-吡咯啉-5-羧酸脱氢酶可能是鸟氨酸-谷氨酸途径中的一种调节酶。
