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使用CardioMEMS心力衰竭系统早期检测亚临床主动脉瓣心内膜炎

Early Detection of Subclinical Aortic Valve Endocarditis with the CardioMEMS Heart Failure System.

作者信息

Sarsam Sinan, Kaspar Georgy, David Shukri, Zughaib Marcel

机构信息

Department of Cardiology, Providence Hospital and Medical Centers, Michigan State University, Southfield, MI, USA.

Department of Cardiology,, Providence Hospital and Medical Centers, Michigan State University, Southfield, MI, USA.

出版信息

Am J Case Rep. 2017 Jun 14;18:665-668. doi: 10.12659/ajcr.903071.

DOI:10.12659/ajcr.903071
PMID:28611348
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5478220/
Abstract

BACKGROUND The CardioMEMS Heart Failure System is a well validated tool to optimize management of systolic and diastolic heart failure and has been shown to reduce the risk of hospitalization by 37%. We are reporting a unique case of acute aortic valve insufficiency as a first sign of endocarditis, detected early in a patient with the CardioMEMS device. CASE REPORT A 79-year-old man with dual bioprosthetic mitral and aortic valve replacement and non-ischemic cardiomyopathy had a CardioMEMS Heart Failure System implanted 2 months following valve replacement surgery. The CardioMEMS System detected a gradual but steady increase in the pulmonary artery pressures while the patient was completely asymptomatic. A transthoracic echocardiogram demonstrated evidence of severe aortic valve regurgitation and mobile vegetation. The diagnosis of infective endocarditis was made with evidence of methicillin-sensitive Staphylococcus aureus bacteremia and involvement of the bioprosthetic aortic valve. The patient ultimately underwent treatment with intravenous antibiotics and redo aortic valve replacement. CONCLUSIONS While the CardioMEMS Heart Failure System is effective in reducing readmission rates for patients with class III heart failure, it can detect early hemodynamic changes from conditions other than congestive heart failure. Our case illustrated the CardioMEMS-assisted early diagnosis of infective endocarditis prior to clinical deterioration.

摘要

背景

CardioMEMS心力衰竭系统是一种经过充分验证的工具,可优化收缩性和舒张性心力衰竭的管理,并已证明可将住院风险降低37%。我们报告了一例独特的病例,一名植入CardioMEMS设备的患者早期检测到急性主动脉瓣关闭不全作为心内膜炎的首发症状。病例报告:一名79岁男性,接受了二尖瓣和主动脉瓣双生物瓣置换术以及非缺血性心肌病治疗,在瓣膜置换手术后2个月植入了CardioMEMS心力衰竭系统。在患者完全无症状的情况下,CardioMEMS系统检测到肺动脉压力逐渐但稳定地升高。经胸超声心动图显示存在严重主动脉瓣反流和活动赘生物。根据甲氧西林敏感金黄色葡萄球菌菌血症及生物瓣主动脉瓣受累的证据,诊断为感染性心内膜炎。患者最终接受了静脉抗生素治疗及再次主动脉瓣置换术。结论:虽然CardioMEMS心力衰竭系统在降低III级心力衰竭患者的再入院率方面有效,但它可以检测到除充血性心力衰竭以外的其他疾病引起的早期血流动力学变化。我们的病例说明了CardioMEMS辅助在临床恶化之前对感染性心内膜炎进行早期诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e7f/5478220/32af77f58e21/amjcaserep-18-665-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e7f/5478220/74478dbff41d/amjcaserep-18-665-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e7f/5478220/32af77f58e21/amjcaserep-18-665-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e7f/5478220/74478dbff41d/amjcaserep-18-665-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e7f/5478220/32af77f58e21/amjcaserep-18-665-g002.jpg

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本文引用的文献

1
Impact of Practice-Based Management of Pulmonary Artery Pressures in 2000 Patients Implanted With the CardioMEMS Sensor.2000 例植入 CardioMEMS 传感器患者的肺动脉压力基于实践管理的影响。
Circulation. 2017 Apr 18;135(16):1509-1517. doi: 10.1161/CIRCULATIONAHA.116.026184. Epub 2017 Feb 20.
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Pulmonary Artery Pressure-Guided Heart Failure Management Reduces 30-Day Readmissions.肺动脉压引导的心力衰竭管理可降低30天再入院率。
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Remote heart function monitoring: role of the CardioMEMS HF System.
J Cardiovasc Med (Hagerstown). 2016 Jul;17(7):518-23. doi: 10.2459/JCM.0000000000000367.
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