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一例非根治性切除胃癌患者采用替吉奥单药术后化疗实现8年以上长期生存

A Case of Noncuratively Resected Gastric Cancer and Postoperative Chemotherapy with S-1 Monotherapy Resulting in Long-Term Survival for Over 8 Years.

作者信息

Suh Byoung Jo

机构信息

Department of Surgery, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.

出版信息

Case Rep Oncol. 2017 Feb 28;10(1):217-225. doi: 10.1159/000460290. eCollection 2017 Jan-Apr.

DOI:10.1159/000460290
PMID:28611634
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5465688/
Abstract

We report the case of a noncuratively resected gastric cancer patient who was successfully treated with S-1 monotherapy, resulting in long-term survival of 96 months. A 72-year-old woman underwent noncurative resection of subtotal gastrectomy for advanced gastric cancer with conglomerated lymph node metastasis and pancreatic invasion. She received chemotherapy with S-1 monotherapy postoperatively. S-1 (100 mg/day) was administered orally after breakfast and dinner for 28 days followed by a 14-day break for a total of 52 months. Regular checkups with esophagogastroduodenoscopy, abdominopelvic computed tomography, and fluorine-18-fluorodeoxyglucose positron emission tomography revealed no evidence of cancer 96 months after the operation. The patient was effectively treated with long-term administration of S-1 after noncurative gastrectomy for advanced gastric cancer.

摘要

我们报告了一例非根治性切除的胃癌患者，该患者接受S-1单药治疗成功，实现了96个月的长期生存。一名72岁女性因晚期胃癌伴融合性淋巴结转移和胰腺侵犯接受了非根治性次全胃切除术。术后她接受了S-1单药化疗。S-1（100毫克/天）在早餐和晚餐后口服，持续28天，随后休息14天，共进行52个月。术后96个月，通过食管胃十二指肠镜检查、腹盆腔计算机断层扫描和氟-18-氟脱氧葡萄糖正电子发射断层扫描进行定期检查，未发现癌症迹象。该晚期胃癌患者在非根治性胃切除术后长期服用S-1得到了有效治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a92d/5465688/bbf9a32ae18c/cro-0010-0217-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a92d/5465688/a137979679ba/cro-0010-0217-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a92d/5465688/b340f3ccfd87/cro-0010-0217-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a92d/5465688/272b5cd383cd/cro-0010-0217-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a92d/5465688/a5e96030b3b9/cro-0010-0217-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a92d/5465688/bbf9a32ae18c/cro-0010-0217-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a92d/5465688/a137979679ba/cro-0010-0217-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a92d/5465688/b340f3ccfd87/cro-0010-0217-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a92d/5465688/272b5cd383cd/cro-0010-0217-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a92d/5465688/a5e96030b3b9/cro-0010-0217-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a92d/5465688/bbf9a32ae18c/cro-0010-0217-g05.jpg

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本文引用的文献

1
Prognostic Discrepancy of the 6th and 7th UICC N Classification for Lymph Node Staging in Gastric Cancer Patients after Curative Resection.根治性切除术后胃癌患者第6版和第7版国际抗癌联盟（UICC）淋巴结分期N分类的预后差异
Case Rep Oncol. 2017 Jan 17;10(1):57-65. doi: 10.1159/000455189. eCollection 2017 Jan-Apr.
2
Gastrectomy plus chemotherapy versus chemotherapy alone for advanced gastric cancer with a single non-curable factor (REGATTA): a phase 3, randomised controlled trial.胃切除术加化疗与单纯化疗治疗有单一不可治愈因素的晚期胃癌（REGATTA）：一项 3 期随机对照试验。
Lancet Oncol. 2016 Mar;17(3):309-318. doi: 10.1016/S1470-2045(15)00553-7. Epub 2016 Jan 26.
3
Clinicopathologic characteristics of gastric cancer patients who underwent noncurative gastrectomy with long-term survival.
接受非根治性胃切除术且长期存活的胃癌患者的临床病理特征
Langenbecks Arch Surg. 2009 Jan;394(1):99-103. doi: 10.1007/s00423-008-0398-z. Epub 2008 Aug 2.
4
Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine.使用口服氟嘧啶S-1对胃癌进行辅助化疗。
N Engl J Med. 2007 Nov 1;357(18):1810-20. doi: 10.1056/NEJMoa072252.
5
Efficacy of S-1 for patients with peritoneal metastasis of gastric cancer.S-1对胃癌腹膜转移患者的疗效。
Chemotherapy. 2006;52(6):301-7. doi: 10.1159/000096002. Epub 2006 Sep 29.
6
Long-term outcome of S-1 and cisplatin combination therapy in patients with advanced or recurrent gastric cancer.S-1与顺铂联合治疗晚期或复发性胃癌患者的长期疗效
Gastric Cancer. 2005;8(2):111-6. doi: 10.1007/s10120-004-0313-4.
7
A new perspective on cardiotoxicity of 5-fluorouracil. A novel research tool 'cardiac ultrasonic integrated backscatter analysis' indicates transient, subclinical myocardial dysfunction due to high-dose leucovorin and infusional 5-fluorouracil regimen.
Chemotherapy. 2004 Jun;50(3):113-8. doi: 10.1159/000077884.
8
Defining palliative surgery in patients receiving noncurative resections for gastric cancer.定义接受非根治性胃癌切除术患者的姑息性手术。
J Am Coll Surg. 2004 Jun;198(6):1013-21. doi: 10.1016/j.jamcollsurg.2004.02.007.
9
Value of palliative resection in gastric cancer.胃癌姑息性切除的价值。
Br J Surg. 2002 Nov;89(11):1438-43. doi: 10.1046/j.1365-2168.2002.02220.x.
10
Global cancer statistics in the year 2000.2000年全球癌症统计数据。
Lancet Oncol. 2001 Sep;2(9):533-43. doi: 10.1016/S1470-2045(01)00486-7.