Serwin Agnieszka Beata, Bulhak-Koziol Violetta, Sokolowska Marianna, Golparian Daniel, Unemo Magnus
Department of Dermatology and Venereology, Medical University of Bialystok, Bialystok, Poland.
Diagnostic and Research Centre for Sexually Transmitted Diseases, Bialystok, Poland.
APMIS. 2017 Sep;125(9):840-843. doi: 10.1111/apm.12713. Epub 2017 Jun 14.
Trichomonas vaginalis is the most common curable sexually transmitted pathogen globally. However, in the European Union (EU), trichomoniasis appears to be a rare condition. The aim of this study was to examine the prevalence of T. vaginalis among females attending an STI centre in Bialystok, Poland, using the highly sensitive and specific APTIMA T. vaginalis assay. Consecutive females, referred by gynaecologists mainly because of abnormal vaginal discharge, were diagnosed using wet mount microscopy, culture and APTIMA T. vaginalis assay. Among 272 women studied, 82% were pre- and 18% postmenopausal. The average age was 36.0 ± 13.9 (range: 18-86) years. Abnormal discharge (alone or accompanied by itch or vulvovaginal burning) was the most frequent complain in both groups (66.2% and 48.0%). Erythema and discharge were the most frequent abnormal signs (58.6% and 56.0%). Not a single T. vaginalis-positive sample was detected using wet mount microscopy, culture or APTIMA T. vaginalis assay. Despite using the highly sensitive APTIMA T. vaginalis assay for detection, the pathogen could not be identified in females in the studied setting, similar to results from other EU settings. The need for general screening using NAAT for this pathogen while diagnosing vulvovaginal symptoms in females in Poland appears to be low.
阴道毛滴虫是全球最常见的可治愈性传播病原体。然而,在欧盟(EU),滴虫病似乎是一种罕见疾病。本研究的目的是使用高度敏感和特异的APTIMA阴道毛滴虫检测法,检测波兰比亚韦斯托克一家性传播感染中心就诊女性中阴道毛滴虫的患病率。主要因阴道分泌物异常由妇科医生转诊的连续女性患者,采用湿片显微镜检查、培养和APTIMA阴道毛滴虫检测法进行诊断。在研究的272名女性中,82%为绝经前女性,18%为绝经后女性。平均年龄为36.0±13.9(范围:18 - 86)岁。两组中最常见的主诉都是分泌物异常(单独出现或伴有瘙痒或外阴阴道烧灼感)(分别为66.2%和48.0%)。红斑和分泌物是最常见的异常体征(分别为58.6%和56.0%)。使用湿片显微镜检查、培养或APTIMA阴道毛滴虫检测法均未检测到阴道毛滴虫阳性样本。尽管使用了高度敏感的APTIMA阴道毛滴虫检测法进行检测,但在所研究的环境中,女性体内未发现该病原体,这与其他欧盟地区的结果相似。在波兰,女性诊断外阴阴道症状时,对该病原体进行核酸扩增检测(NAAT)进行普遍筛查的必要性似乎较低。