Shoja Mohammadali M, Johal Jaspreet, Oakes W Jerry, Tubbs R Shane
Department of Neurosciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Anatomical Sciences, St. George's University, School of Medicine Grenada, West Indies.
Clin Anat. 2018 Mar;31(2):202-215. doi: 10.1002/ca.22939. Epub 2017 Dec 4.
Although the Chiari malformations are well-studied and described developmental anomalies, there remains some incongruity in regards to their underlying etiologies. A number of theories have been proposed with the purpose of accounting for the embryology and pathogenesis of the Chiari I and II malformations and their associated complications and clinical syndromes. The present review aims to review the pertinent literature for all of the main theories that have been proposed, and outline their validity and relevance to our contemporary understanding of these anomalies. Clin. Anat. 31:202-215, 2018. © 2017 Wiley Periodicals, Inc.
尽管Chiari畸形是经过充分研究和描述的发育异常，但关于其潜在病因仍存在一些不一致之处。已经提出了许多理论，目的是解释Chiari I型和II型畸形的胚胎学和发病机制及其相关并发症和临床综合征。本综述旨在回顾已提出的所有主要理论的相关文献，并概述它们的有效性以及与我们当代对这些异常的理解的相关性。《临床解剖学》2018年第31卷：202 - 215页。© 2017威利期刊公司。
