Swedish Agency for Health Technology Assessment and Assessment of Social
Department of Dental Medicine,Karolinska Institutet,Department of Oral and Maxillofacial Surgery,Karolinska University Hospital.
Int J Technol Assess Health Care. 2017 Jan;33(1):93-102. doi: 10.1017/S026646231700023X.
The aim of this study was to evaluate available knowledge and identify knowledge gaps within the field of oral and maxillofacial surgery, by systematically collecting and evaluating systematic reviews. Twelve specific domains were selected: surgical removal of teeth, antibiotic and corticosteroid prophylaxis, orofacial infections, dental and facial trauma, orthognathic surgery, reconstructive surgery, benign tumors, cysts, premalignant lesions, oral complications of treatment of malignant tumors, hyperbaric oxygen therapy, temporomandibular joint surgery, cost effectiveness of different surgical treatments, and ethics.
The literature search, covering four databases, was conducted during September 2014: PubMed, The Cochrane library, Centre for Reviews and Dissemination and EBSCO dentistry and oral science source. Retrieved systematic reviews were quality assessed by AMSTAR.
In all, 1,778 abstracts were identified, of which 200 met the inclusion criteria. Forty-five systematic reviews were assessed as of high to moderate quality. The results disclosed some existing evidence in a few domains, such as surgical removal of teeth and implant survival after sinus lifts. However, in all domains, the search revealed a large number of knowledge gaps. Also of concern was the lack of data regarding health economics and ethics.
In conclusion, there is a need for well-conducted clinical research in the fields of oral and maxillofacial surgery.
本研究旨在通过系统地收集和评估系统评价，评估口腔颌面外科学领域的现有知识并确定知识空白。选择了 12 个特定领域：牙齿的外科切除、抗生素和皮质类固醇预防、口腔颌面部感染、牙和面部创伤、正颌外科、重建外科、良性肿瘤、囊肿、癌前病变、恶性肿瘤治疗的口腔并发症、高压氧治疗、颞下颌关节手术、不同手术治疗的成本效益以及伦理学。
文献检索于 2014 年 9 月在四个数据库中进行：PubMed、Cochrane 图书馆、综述与传播中心和 EBSCO 牙科与口腔科学资源。对检索到的系统评价进行了 AMSTAR 质量评估。
共确定了 1778 篇摘要，其中 200 篇符合纳入标准。评估了 45 篇系统评价，其质量为高到中度。结果揭示了一些在几个领域存在的现有证据，如牙齿的外科切除和窦提升后种植体的存活率。然而，在所有领域，检索结果都显示存在大量的知识空白。同样令人关注的是缺乏关于健康经济学和伦理学的数据。
总之，口腔颌面外科学领域需要进行精心设计的临床研究。
