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[与结核病/艾滋病病毒合并感染相关的因素:来自巴西亚马孙州2001 - 2012年报告数据的证据]

[Factors associated with TB/HIV coinfection: evidence from notification data in the State of Amazonas, Brazil, 2001-2012].

作者信息

Magno Evela da Silva, Saraceni Valeria, Souza Alexandra Brito de, Magno Regma da Silva, Saraiva Maria das Graças Gomes, Bührer-Sékula Samira

机构信息

Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brasil.

Secretaria Municipal de Saúde do Rio de Janeiro, Rio de Janeiro, Brasil.

出版信息

Cad Saude Publica. 2017 Jun 12;33(5):e00019315. doi: 10.1590/0102-311X00019315.

DOI:10.1590/0102-311X00019315
PMID:28614446
Abstract

Tuberculosis (TB) in persons living with HIV (PLHIV) is the leading infectious cause of AIDS-related death. The aim of this study was to estimate the prevalence of TB/HIV coinfection, evaluate notification of the two diseases over time by probabilistic database linkage, and identify factors associated with AIDS and TB notifications. Prevalence of TB/HIV coinfection was 7.7%. The group of PLHIV with subsequent TB diagnosis was the most representative, despite available preventive measures. Underreporting of TB among AIDS cases was 35%, and 19.6% of TB cases could have been reported as AIDS. For AIDS cases with mention of TB, living in the state capital showed 75% greater odds of being reported to the Tuberculosis Notification System (SINAN-TB), and having died increased the odds of reporting by 40%. Of TB cases with mention of HIV, brown skin color, age 25 to 39 years, living in the state capital, and having evolved to death were associated with higher odds of reporting to the AIDS Notification System. Periodic linkage of these databases can be a powerful tool for programs to decrease underreporting.

摘要

艾滋病毒感染者(PLHIV)中的结核病是艾滋病相关死亡的主要感染原因。本研究的目的是估计结核病/艾滋病毒合并感染的患病率,通过概率数据库链接评估两种疾病随时间的报告情况,并确定与艾滋病和结核病报告相关的因素。结核病/艾滋病毒合并感染的患病率为7.7%。尽管有可用的预防措施,但随后被诊断出患有结核病的艾滋病毒感染者群体最具代表性。艾滋病病例中结核病的漏报率为35%,19.6%的结核病病例本可作为艾滋病病例报告。对于提及结核病的艾滋病病例,居住在州首府的病例被报告至结核病通报系统(SINAN-TB)的几率高75%,而死亡病例的报告几率增加40%。在提及艾滋病毒的结核病病例中,棕色皮肤、年龄在25至39岁、居住在州首府以及病情发展至死亡与向艾滋病通报系统报告的几率较高相关。这些数据库的定期链接可以成为各项目减少漏报的有力工具。

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