Saraceni Valeria, Pereira Gerson Fernando Mendes, da Silveira Mariangela Freitas, Araujo Maria Alix Leite, Miranda Angelica Espinosa
Secretaria Municipal de Saúde do Rio de Janeiro, Superintendência de Vigilância em Saúde, Rio de Janeiro (RJ), Brasil.
Ministério da Saúde, Secretaria de Vigilância em Saúde, Departamento de DST/AIDS, Brasília (DF), Brasil.
Rev Panam Salud Publica. 2017 Jun 8;41:e44. doi: 10.26633/RPSP.2017.44.
To describe the epidemiological profile of reported cases of syphilis in pregnancy and congenital syphilis in five states (Amazonas, Ceará, Espírito Santo, Rio de Janeiro, and Rio Grande do Sul) and the Federal District using data from the Reportable Disease Information System (SINAN).
This descriptive study including an ecological and cross-sectional evaluation employed data from SINAN Net. The syphilis detection rate in pregnancy and the congenital syphilis incidence rate per 1 000 live births were calculated. To identify pregnant women with syphilis who had an outcome of congenital syphilis, the two SINAN databases were linked using the RecLink software. Because the data were representative at the state (not national) level, comparisons were made between the units of the federation and not with the sum of cases.
A growth in the syphilis detection rate in pregnancy was detected, ranging from 21% (Amazonas) to 75% (Rio de Janeiro) during the study period. The incidence of congenital syphilis followed the same trend of growth (ranging from 35.6% in the Federal District to 63.9% in Rio Grande do Sul), except for a 0.7% decline in Amazonas. The proportion of women with an outcome of congenital syphilis who had prenatal care ranged from 67.3% in Amazonas to 83.3% in the Federal District. Of the pregnant women with syphilis, 43% had an outcome of congenital syphilis. In pregnant women with syphilis and an outcome of congenital syphilis, maternal diagnosis was made prenatally in 74% and at delivery in 18%. The moment of diagnosis was ignored in 8% of the women.
The increase in the syphilis detection rate may have resulted from an increase in the report rate. Ongoing monitoring of pregnant women is essential to eliminate syphilis.
利用法定传染病信息系统（SINAN）的数据，描述五个州（亚马孙州、塞阿拉州、圣埃斯皮里图州、里约热内卢州和南里奥格兰德州）以及联邦区报告的妊娠梅毒和先天性梅毒病例的流行病学概况。
这项描述性研究包括生态和横断面评估，采用了SINAN Net的数据。计算了妊娠梅毒检测率和每1000例活产儿的先天性梅毒发病率。为了确定患有先天性梅毒的梅毒孕妇，使用RecLink软件将两个SINAN数据库进行了关联。由于数据仅在州（而非国家）层面具有代表性，因此是在联邦各单位之间进行比较，而非与病例总数进行比较。
在研究期间，检测到妊娠梅毒检测率有所增长，范围从21%（亚马孙州）到75%（里约热内卢州）。先天性梅毒发病率也呈现相同的增长趋势（从联邦区的35.6%到南里奥格兰德州的63.9%），但亚马孙州下降了0.7%。患有先天性梅毒的孕妇接受产前护理的比例从亚马孙州的67.3%到联邦区的83.3%不等。在患有梅毒的孕妇中，43%产下患有先天性梅毒的婴儿。在患有梅毒且产下患有先天性梅毒婴儿的孕妇中，74%在产前被诊断出，18%在分娩时被诊断出。8%的女性未提及诊断时间。
梅毒检测率的上升可能是报告率增加所致。持续监测孕妇对于消除梅毒至关重要。
