García-Seara Javier, Gude Sampedro Francisco, Martínez Sande Jose L, Fernández López Xesus Alberte, Rodríguez Mañero Moisés, González Melchor Laila, Alvarez Alvarez Belén, Iglesias Alvarez Diego, González Juanatey José Ramón
Unidad de Arritmias, Servicio de Cardiología, Hospital Clínico y Universitario de Santiago de Compostela, Spain.
Unidad de Epidemiología, Servicio de Cardiología, Hospital Clínico y Universitario de Santiago de Compostela, Spain.
Int J Cardiol Heart Vasc. 2016 Jun 1;12:88-94. doi: 10.1016/j.ijcha.2016.05.006. eCollection 2016 Sep.
We determined the effectiveness of the HATCH score in patients with typical atrial flutter (AFl) undergoing cavotricuspid isthmus (CTI) ablation to predict long-term atrial fibrillation (AF).
We conducted an observational retrospective single-center cohort study including all patients admitted to our hospital for a CTI ablation between 1998 and 2010. The patients were divided into four categories: 1) new-onset AF (no prior AF and AF during follow-up (FU)); 2) old AF (prior AF and no AF during FU); 3) prior and post AF (AF prior and post CTI ablation); and 4) no AF.
Four hundred and eight patients were included. In patients without prior AF, the hazard ratio (HR) for new-onset AF during FU was 0.98 (CI 95%: 0.65-1.50; p = 0.95) and 1.00 (CI 95%: 0.57-1.77; p = 0.98) for HATCH ≥ 2 and HATCH ≥ 3, respectively. In patients with prior AF, the HR for AF was 1.41 (CI 95%: 0.87-2.28; p = 0.17) and 1.79 (CI 95%: 0.96-3.35; p = 0.06), for HATCH ≥ 2 and HATCH ≥ 3, respectively. Left atrial enlargement was positively correlated with the occurrence of AF during FU, especially in the subgroup without prior AF, which had a HR of 2.44 (CI 95%: 1.35-4.40; p = 0.003), a HR of 2.88 (CI 95%: 1.36-6.10; p = 0.006) and a HR of 3.68 (CI 95%: 1.71-7.94; p = 0.001), for slight, moderate and severely dilated left atrial dimension, respectively, compared with a normal value.
HATCH score did not predict AF in patients with typical AFl who underwent CTI ablation. Basal left atrium dimension could help predict new-onset AF.
我们确定了HATCH评分在接受三尖瓣峡部(CTI)消融的典型心房扑动(AFl)患者中预测长期心房颤动(AF)的有效性。
我们进行了一项观察性回顾性单中心队列研究,纳入了1998年至2010年间在我院接受CTI消融的所有患者。患者分为四类:1)新发房颤(既往无房颤且随访(FU)期间发生房颤);2)陈旧性房颤(既往有房颤且FU期间无房颤);3)消融前后均有房颤(CTI消融前后均有房颤);4)无房颤。
共纳入408例患者。在无既往房颤的患者中,FU期间新发房颤的风险比(HR)对于HATCH≥2和HATCH≥3分别为0.98(95%CI:0.65 - 1.50;p = 0.95)和1.00(95%CI:0.57 - 1.77;p = 0.98)。在有既往房颤的患者中,房颤的HR对于HATCH≥2和HATCH≥3分别为1.41(95%CI:0.87 - 2.28;p = 0.17)和1.79(95%CI:0.96 - 3.35;p = 0.06)。左心房扩大与FU期间房颤的发生呈正相关,尤其是在无既往房颤的亚组中,与正常左心房大小相比,轻度、中度和重度左心房扩大时房颤的HR分别为2.44(95%CI:1.35 - 4.40;p = 0.003)、2.88(95%CI:1.36 - 6.10;p = 0.006)和3.68(95%CI:1.71 - 7.94;p = 0.001)。
HATCH评分不能预测接受CTI消融的典型AFl患者的房颤发生。基础左心房大小有助于预测新发房颤。