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钕钇铝石榴石激光治疗直肠和阴道静脉畸形

Nd:YAG laser therapy for rectal and vaginal venous malformations.

作者信息

Gurien Lori A, Jackson Richard J, Kiser Michelle M, Richter Gresham T

机构信息

Department of Pediatric Surgery, Arkansas Children's Hospital, 1 Children's Way, Slot 837, Little Rock, AR, 72202, USA.

Department of Pediatric Surgery, Arkansas Children's Hospital Research Institute, 13 Children's Way, Little Rock, AR, 72202, USA.

出版信息

Pediatr Surg Int. 2017 Aug;33(8):887-891. doi: 10.1007/s00383-017-4113-4. Epub 2017 Jun 14.

Abstract

BACKGROUND

Limited therapeutic options exist for rectal and vaginal venous malformations (VM). We describe our center's experience using Nd:YAG laser for targeted ablation of abnormal veins to treat mucosally involved pelvic VM.

METHODS

Records of patients undergoing non-contact Nd:YAG laser therapy of pelvic VM at a tertiary children's hospital were reviewed. Symptoms, operative findings and details, complications, and outcomes were evaluated.

RESULTS

Nine patients (age 0-24) underwent Nd:YAG laser therapy of rectal and/or vaginal VM. Rectal bleeding was present in all patients and vaginal bleeding in all females (n = 5). 5/7 patients had extensive pelvic involvement on MRI. Typical settings were 30 (rectum) and 20-25 W (vagina), with 0.5-1.0 s pulse duration. Patients underwent the same-day discharge. Treatment intervals ranged from 14 to 180 (average = 56) weeks, with 6.1-year mean follow-up. Five patients experienced symptom relief with a single treatment. Serial treatments managed recurrent bleeding successfully in all patients, with complete resolution of vaginal lesions in 40% of cases. No complications occurred.

CONCLUSIONS

Nd:YAG laser treatment of rectal and vaginal VM results in substantial improvement and symptom control, with low complication risk. Given the high morbidity of surgical resection, Nd:YAG laser treatment of pelvic VM should be considered as first line therapy.

摘要

背景

直肠和阴道静脉畸形(VM)的治疗选择有限。我们描述了我们中心使用Nd:YAG激光对异常静脉进行靶向消融以治疗累及黏膜的盆腔VM的经验。

方法

回顾了一家三级儿童医院接受盆腔VM非接触Nd:YAG激光治疗的患者记录。评估了症状、手术发现及细节、并发症和治疗结果。

结果

9例患者(年龄0 - 24岁)接受了直肠和/或阴道VM的Nd:YAG激光治疗。所有患者均有直肠出血,所有女性患者(n = 5)均有阴道出血。5/7患者在MRI上有广泛的盆腔受累。典型参数设置为直肠30W、阴道20 - 25W,脉冲持续时间0.5 - 1.0秒。患者当日出院。治疗间隔时间为14至180周(平均 = 56周),平均随访6.1年。5例患者单次治疗后症状缓解。所有患者经系列治疗成功控制了复发性出血,40%的病例阴道病变完全消退。未发生并发症。

结论

Nd:YAG激光治疗直肠和阴道VM可显著改善症状并实现症状控制,并发症风险低。鉴于手术切除的高发病率,Nd:YAG激光治疗盆腔VM应被视为一线治疗方法。

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