Fitzgerald Mark, Esser Max, Russ Matthias, Mathew Joseph, Varma Dinesh, Wilkinson Andrew, Mannambeth Rejith V, Smit Devilliers, Bernard Stephen, Mitra Biswadev
Trauma Service, Alfred Hospital, Melbourne, Victoria, Australia.
National Trauma Research Institute, Monash University, Melbourne, Victoria, Australia.
Emerg Med Australas. 2017 Aug;29(4):444-449. doi: 10.1111/1742-6723.12820. Epub 2017 Jun 14.
A multidisciplinary approach that emphasised improved triage, early pelvic binder application, early administration of blood and blood products, adherence to algorithmic pathways, screening with focused sonography (FAST), early computed tomography scanning with contrast angiography, angio-embolisation and early operative intervention by specialist pelvic surgeons was implemented in the last decade to improve outcomes after pelvic trauma. The manuscript evaluated the effect of this multi-faceted change over a 12-year period.
A retrospective cohort study was conducted comparing patients presenting with serious pelvic injury in 2002 to those presenting in 2013. The primary exposure and comparator variables were the year of presentation and the primary outcome variable was mortality at hospital discharge. Potential confounders were evaluated using multivariable logistic regression analysis.
There were 1213 patients with a serious pelvic injury (Abbreviated Injury Scale ≥3), increasing from 51 in 2002 to 156 in 2013. Demographics, injury severity and presenting clinical characteristics were similar between the two time periods. There was a statistically significant difference in mortality from 20% in 2002 to 7.7% in 2013 (P = 0.02). The association between the primary exposure variable of being injured in 2013 and mortality remained statistically significant (adjusted odds ratio 0.10; 95% confidence interval: 0.02-0.60) when adjusted for potential clinically important confounders.
Multi-faceted interventions directed at the spectrum of trauma resuscitation from pre-hospital care to definitive surgical management were associated with significant reduction in mortality of patients with severe pelvic injury from 2002 to 2013. This demonstrates the effectiveness of an integrated, inclusive trauma system in achieving improved outcomes.
在过去十年中实施了一种多学科方法,该方法强调改进分诊、早期应用骨盆固定带、早期输注血液及血液制品、遵循算法流程、采用聚焦超声(FAST)进行筛查、早期进行增强血管造影的计算机断层扫描、血管栓塞以及由专业骨盆外科医生进行早期手术干预,以改善骨盆创伤后的治疗效果。本文评估了这一多方面改变在12年期间的效果。
进行了一项回顾性队列研究,比较2002年和2013年出现严重骨盆损伤的患者。主要暴露变量和对照变量为就诊年份,主要结局变量为出院时的死亡率。使用多变量逻辑回归分析评估潜在混杂因素。
共有1213例严重骨盆损伤患者(简明损伤定级标准≥3级),从2002年的51例增加到2013年的156例。两个时间段的人口统计学、损伤严重程度和就诊时的临床特征相似。死亡率有统计学显著差异,从2002年的20%降至2013年的7.7%(P = 0.02)。在对潜在的具有临床重要意义的混杂因素进行调整后,2013年受伤这一主要暴露变量与死亡率之间的关联仍具有统计学显著性(调整后的比值比为0.10;95%置信区间:0.02 - 0.60)。
从院前护理到确定性手术管理的一系列创伤复苏多方面干预措施与2002年至2013年期间严重骨盆损伤患者死亡率的显著降低相关。这证明了一个综合、包容的创伤系统在改善治疗效果方面的有效性。