Department of Pediatric Cardiology, Poznań University of Medical Sciences, Poznań, Poland.
Eur Rev Med Pharmacol Sci. 2017 May;21(10):2550-2559.
Numerous restrictions, which are imposed on children with arrhythmia, influence their quality of life (QoL) and may have a negative impact on their further development. Ablation is a highly successful treatment leaving patients free from arrhythmia and other related limitations. There are very few studies evaluating the influence of ablation on the QoL in children with arrhythmia, based on small groups of patients. The aim of this study was to evaluate the impact of ablation on the QoL in children with supraventricular tachycardia (SVT).
We included 122 children with SVT who underwent a successful ablation. The Qol was assessed before and after the ablation, using the WHOQOL-BREF and the Pediatric Arrhythmia Related Score (PARS) - a specific questionnaire developed by the authors.
Six months after the ablation, WHOQOL-BREF showed a significant improvement in the QoL in the physical (Phd) (p < 0.0001), psychological (Psd) (p = 0.0014) and social relationships (SRD) (p = 0.0165) domains. PARS showed a significant improvement in the QoL in the Phd (p < 0.0001), Psd (p = 0.0307) and medical satisfaction domains (Msd) (p < 0.0001). No improvement in Psd was revealed in children who had been off medications before the ablation. In the youngest children, a significant improvement was observed in all the measured domains in both questionnaires (p < 0.05), while in older children the greatest improvement after the ablation was noted in the area of physical functioning.
Ablation in children with SVT significantly improved general satisfaction with health and with the QoL and had a positive impact on QoL scores. The youngest patients and those on antiarrhythmic medication before the ablation, benefit most from the procedure.
心律失常患儿存在诸多限制,影响其生活质量(QoL),并可能对其进一步发展产生负面影响。消融术是一种非常成功的治疗方法,可以使患者免受心律失常和其他相关限制的影响。基于小样本量患者的研究,评估消融术对心律失常患儿 QoL 影响的研究非常少。本研究旨在评估消融术对儿童室上性心动过速(SVT)患者 QoL 的影响。
我们纳入了 122 例成功接受消融术的 SVT 患儿。使用 WHOQOL-BREF 和作者开发的特定问卷——儿科心律失常相关评分(PARS),在消融术前后评估 QoL。
消融术后 6 个月,WHOQOL-BREF 在生理领域(Phd)(p<0.0001)、心理领域(Psd)(p=0.0014)和社会关系领域(SRD)(p=0.0165)的 QoL 显著改善。PARS 在 Phd(p<0.0001)、Psd(p=0.0307)和医疗满意度领域(Msd)(p<0.0001)的 QoL 显著改善。消融术前已停药的患儿,Psd 未见改善。在年龄最小的患儿中,两个问卷的所有测量领域均显示出显著改善(p<0.05),而在年龄较大的患儿中,消融术后的 QoL 最大改善发生在生理功能领域。
SVT 患儿的消融术显著提高了对健康和 QoL 的总体满意度,并对 QoL 评分产生了积极影响。年龄最小的患儿和消融术前使用抗心律失常药物的患儿,最能从该治疗中获益。