Effects of acute and varying amounts of alcohol consumption on alkaline phosphatase, aspartate transaminase, and gamma-glutamyltransferase.

Acute alcohol consumption has no effect on the levels of enzymes in serum. Regardless of the amount consumed, no significant changes in serum enzymes were observed. Age-related differences in gamma-glutamyltransferase were not apparent. Peak blood alcohol concentration and consumption are not related to the body mass. Screening of drunk drivers for detecting problem drinkers could be undertaken by performing biochemical measurements of serum enzymes, especially gamma-glutamyltransferase.