Ado A D, Gol'dshteĭn M M, Dontsov V I
Biull Eksp Biol Med. 1985 Jul;100(7):46-8.
A study was made of the effects of the neurotransmitters acetylcholine and adrenaline on proliferation of B lymphocytes of mice immunized with ovalbumin. The neurotransmitters were noticed to be capable of changing B cell proliferation on cultivation in vitro. The effect (an increase or reduction of 3H-thymidine incorporation) depended on the time of immunization, antigen dose, and the type of a neurotransmitter. On the whole the pattern of the acetylcholine effect correlated with a natural trend of changes in B lymphocyte proliferation at different times of the immune response. Adrenaline produced a reciprocal effect.
研究了神经递质乙酰胆碱和肾上腺素对用卵清蛋白免疫的小鼠B淋巴细胞增殖的影响。发现这些神经递质能够在体外培养时改变B细胞增殖。其作用（3H-胸腺嘧啶核苷掺入的增加或减少）取决于免疫时间、抗原剂量和神经递质类型。总体而言，乙酰胆碱的作用模式与免疫反应不同时间B淋巴细胞增殖变化的自然趋势相关。肾上腺素则产生相反的作用。
