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一名肾移植患者发生的静脉注射免疫球蛋白相关无菌性脑膜炎

IVIG Associated Aseptic Meningitis in a Renal Transplant Patient.

作者信息

Wanigasekera Tamara, Grainger Rachel J, Sexton Donal J, Magee Colm

机构信息

Transplant, Urology and Nephrology Directorate, Beaumont Hospital, Dublin 9, Ireland.

Department of Clinical Microbiology, Beaumont Hospital, Dublin 9, Ireland.

出版信息

Case Rep Transplant. 2017;2017:6962150. doi: 10.1155/2017/6962150. Epub 2017 May 23.

DOI:10.1155/2017/6962150
PMID:28620559
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5460409/
Abstract

The management of antibody-mediated rejection in renal transplant recipients involves plasmapheresis with IVIG. Aseptic meningitis is a rare adverse effect of IVIG therapy and is a diagnosis of exclusion. We report a case of a renal transplant patient who developed IVIG associated aseptic meningitis in the context of management of antibody-mediated rejection, four years after transplantation.

摘要

肾移植受者抗体介导性排斥反应的管理包括静脉注射免疫球蛋白（IVIG）的血浆置换疗法。无菌性脑膜炎是IVIG治疗罕见的不良反应，是一种排除性诊断。我们报告一例肾移植患者，在移植四年后，于抗体介导性排斥反应的管理过程中发生了与IVIG相关的无菌性脑膜炎。

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Clinical characteristics of aseptic meningitis induced by intravenous immunoglobulin in patients with Kawasaki disease.川崎病患儿静脉注射免疫球蛋白致无菌性脑膜炎的临床特征。
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Human intravenous immunoglobulin-induced aseptic meningitis: a case report.人静脉注射免疫球蛋白诱发无菌性脑膜炎：一例报告
J Clin Pharmacol. 2012 Feb;52(2):279-81. doi: 10.1177/0091270010394183.
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Repeated, severe headache in a lung transplant patient: a case report.
Acta Clin Belg. 2010 Jul-Aug;65(4):269-70. doi: 10.1179/acb.2010.057.
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Aseptic meningitis and abducens nerve palsy as a serious side effect of high dose intravenous immunoglobulin used in a patient with renal transplantation.无菌性脑膜炎和外展神经麻痹作为高剂量静脉注射免疫球蛋白用于肾移植患者时的严重副作用。
Transpl Infect Dis. 2008 Jul;10(4):294-7. doi: 10.1111/j.1399-3062.2007.00294.x. Epub 2007 Dec 13.