特应性皮炎和银屑病中的“炎症性皮肤进行曲”。
"Inflammatory skin march" in atopic dermatitis and psoriasis.
机构信息
Department of Dermatology, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka, 812-8582, Japan.
Department of Dermatology, St. Marianna University School of Medicine, Kawasaki, Japan.
出版信息
Inflamm Res. 2017 Oct;66(10):833-842. doi: 10.1007/s00011-017-1065-z. Epub 2017 Jun 15.
BACKGROUND
Comorbidities of cardiovascular diseases (CVDs), metabolic syndrome and autoimmune diseases with systemic inflammation are recent topics in medicine. Inflammatory skin diseases such as atopic dermatitis and psoriasis are an active source of diverse proinflammatory cytokines and chemokines, which are readily detectable in the circulation and are likely to be involved in developing comorbidities.
EVIDENCE
Both atopic dermatitis and psoriasis are frequently comorbid with CVD, metabolic syndrome and autoimmune diseases, the consequence of which is called "inflammatory skin march", "psoriatic march" or "march of psoriasis".
CONCLUSION
In this review, we summarize the epidemiological evidence and pathogenetic concepts regarding inflammatory skin march in atopic dermatitis and psoriasis.
背景
心血管疾病 (CVD)、代谢综合征和伴有全身炎症的自身免疫性疾病的合并症是医学领域的最新课题。特应性皮炎和银屑病等炎症性皮肤病是多种促炎细胞因子和趋化因子的活跃来源，这些细胞因子和趋化因子在循环中很容易被检测到，并且可能与合并症的发生有关。
证据
特应性皮炎和银屑病常与 CVD、代谢综合征和自身免疫性疾病合并，其结果被称为“炎症性皮肤病进行曲”、“银屑病进行曲”或“银屑病进行曲”。
结论
在这篇综述中，我们总结了特应性皮炎和银屑病炎症性皮肤病进行曲的流行病学证据和发病机制概念。
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