只需一勺糖，助你提高耐受性。

Just a Spoonful of Sugar Helps the Tolerance Go Up.

机构信息

Department of Pathology, Committee on Immunology, The University of Chicago, Chicago, IL 60637, USA.

出版信息

Cell. 2017 Jun 15;169(7):1170-1172. doi: 10.1016/j.cell.2017.05.040.

DOI:10.1016/j.cell.2017.05.040

Abstract

Survival of deleterious infections depends significantly on how much stress the affected organism can tolerate. In this issue, Weis et al. find that mice can survive sepsis by maintaining normoglycemia through ferritin's capacity to inactivate Fe ions that otherwise induce free radicals impacting gluconeogenesis in the liver.

摘要

有害感染的存活在很大程度上取决于受感染的生物体能够承受多少压力。在本期杂志中，Weis 等人发现，通过铁蛋白的能力使铁离子失活，从而阻止其产生自由基影响肝脏的糖异生作用，小鼠可以通过维持正常血糖来存活败血症。